Dr. Saul Priceman Yesterday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $9.28 million to Dr. Saul Priceman at City of Hope to conduct a clinical trial for the treatment of breast cancer related brain metastases, which are tumors in the brain that have spread from the original site of the … Continue reading CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases
Breast cancer
Developing a non-toxic approach to bone-crushing cancers
When cancer spreads to the bone the results can be devastating Battling cancer is always a balancing act. The methods we use – surgery, chemotherapy and radiation - can help remove the tumors but they often come at a price to the patient. In cases where the cancer has spread to the bone the treatments … Continue reading Developing a non-toxic approach to bone-crushing cancers
A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer
A Phase 1 clinical trial co-sponsored by CIRM and Oncternal Therapeutics, has started treating patients at UC San Diego (UCSD). The goal of the trial is to test the safety and anti-tumor activity of the Oncternal-developed drug, cirmtuzumab, in treating breast cancer. Breast cancer is the second most common cancer to occur in women, regardless … Continue reading A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer
Stem Cell Roundup: Protein shows promise in treating deadliest form of breast cancer: mosquito spit primes our body for disease
Triple negative breast cancer is more aggressive and difficult to treat than other forms of the disease and, as a result, is more likely to spread throughout the body and to recur after treatment. Now a team at the University of Southern California have identified a protein that could help change that. The research, published … Continue reading Stem Cell Roundup: Protein shows promise in treating deadliest form of breast cancer: mosquito spit primes our body for disease
Stem cell study holds out promise for kidney disease
Kidney failure is the Rodney Dangerfield of diseases, it really doesn’t get the respect it deserves. An estimated 660,000 Americans suffer from kidney failure and around 47,000 people die from it every year. That’s more than die from breast or prostate cancer. But now a new study has identified a promising stem cell candidate that … Continue reading Stem cell study holds out promise for kidney disease
UC Irvine scientists engineer stem cells to “feel” cancer and destroy it
By blocking cell division, chemotherapy drugs take advantage of the fact that cancer cells multiply rapidly in the body. Though this treatment can extend and even save the lives of cancer patients, it’s somewhat like destroying an ant hill with an atomic bomb: there’s a lot of collateral damage. The treatment is infused through the … Continue reading UC Irvine scientists engineer stem cells to “feel” cancer and destroy it
New target for defeating breast cancer stem cells uncovered
Stashed away in most of your tissues and organs lie small populations of adult stem cells. They help keep our bodies functioning properly by replenishing dying or damaged cells. Their ability to make more copies of themselves, as needed, ensures that there’s always an adequate supply set aside. But this very same self-renewing, life-sustaining property … Continue reading New target for defeating breast cancer stem cells uncovered
Sleep inducing hormone puts breast cancer cells to rest
It’s pretty easy to connect the dots between a lack of sleep and an increased risk of a deadly car crash. But what about an increased risk of cancer? A 2012 study of 101 women newly diagnosed with breast cancer found that those with inadequate sleep were more likely to have more aggressive tumors. Though … Continue reading Sleep inducing hormone puts breast cancer cells to rest
Breast cancer: Piecing together early detection and treatment
Developing therapies for disease is kind of like trying to put together a series of incredibly complex puzzles. Scientists collect lots of “puzzle pieces”, in the form of data, through experiments in the lab and clinic or by reading up on other researchers’ results. Each piece gives researchers a tidbit of insight but the breakthroughs … Continue reading Breast cancer: Piecing together early detection and treatment
Stem cell stories that caught our eye: Parkinson’s trial revived, aspirin kills cancer stem cells and a stem cell role in mother-child obesity
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Parkinson’s clinical trials back on track. After nearly 20 years of being stuck on the clinical trial “bookshelf”, an international team from Cambridge, UK revived … Continue reading Stem cell stories that caught our eye: Parkinson’s trial revived, aspirin kills cancer stem cells and a stem cell role in mother-child obesity
The Stem Cellar 