Join the movement to fight rare diseases

Tomorrow, February 28th, is Rare Disease Day. It’s a day to remind ourselves of the millions of people, and their families, struggling with these diseases. These conditions are also called orphan diseases because, in many cases, drug companies were not interested in adopting them to develop treatments. Here at the California Institute for Regenerative Medicine (CIRM), we … Continue reading Join the movement to fight rare diseases

Investing in CAR T-cell therapy to treat cancer

Photo credit: UC Regents  The California Institute for Regenerative Medicine (CIRM) is investing $4 million to support Dr. William Murphy and UC Davis researchers to develop and test a chimeric antigen receptor (CAR) T-cell therapy to treat various B-cell malignancies, ranging from lymphomas to leukemias.  In this Q&A—courtesy of UC Davis Health—Dr. Murphy discusses the importance of T-cell therapy and its implications … Continue reading Investing in CAR T-cell therapy to treat cancer

Finding a treatment for Tay-Sachs disease

The California Institute for Regenerative Medicine (CIRM) has awarded $4,048,253 to Dr. Joseph Anderson and his team at UC Davis to develop a blood stem cell gene therapy for the treatment of Tay-Sachs disease.   Tay-Sachs disease is a rare genetic disorder where a deficiency in the Hex A gene results in excessive accumulation of … Continue reading Finding a treatment for Tay-Sachs disease

Tratando malformaciones congénitas antes del nacimiento 

El bebé, Tobi recibió un tratamiento de células madre, financiado por el CIRM, mientras aún estaba en el útero. To read this blog in English, click here. Michelle y Jeff se llenaron de felicidad cuando se enteraron de que iban a tener un bebé.   Luego, un examen de ultrasonido a las 20 semanas del embarazo … Continue reading Tratando malformaciones congénitas antes del nacimiento 

Making transplants easier for kids, and charting a new approach to fighting solid tumors.

Every year California performs around 100 kidney transplants in children but, on average, around 50 of these patients will have their body reject the transplant. These children then have to undergo regular dialysis while waiting for a new organ. Even the successful transplants require a lifetime of immunosuppression medications. These medications can prevent rejection but … Continue reading Making transplants easier for kids, and charting a new approach to fighting solid tumors.

CIRM Board Approves Funding for New Clinical Trial Targeting Brain Tumors

The governing Board of the California Institute for Regenerative Medicine (CIRM) has awarded almost $12 million to carry out a clinical trial targeting brain tumors. This brings the total number of CIRM funded clinical trials to 83.   $11,999,984 was awarded to Dr. Jana Portnow at the Beckman Research Institute of City of Hope. They are using Neural stem … Continue reading CIRM Board Approves Funding for New Clinical Trial Targeting Brain Tumors

Pioneering a new approach to HIV/AIDS

Dr. Steven Deeks. Photo courtesy UCSF I’ve always been impressed by the willingness of individuals to step forward and volunteer for a clinical trial. Even more so when they are the first person ever to test a first-in-human therapy. They really are pioneers in helping advance a whole new approach to treating disease.  That’s certainly … Continue reading Pioneering a new approach to HIV/AIDS

CIRM-funding supports world’s first stem cell treatment for spina bifida delivered during fetal surgery

Dr. Diana Farmer (right) meets with Emily Lofton and her baby Robbie who had stem cell treatment for spina bifida in the womb. Photo: UC Davis Health The California Institute for Regenerative Medicine (CIRM) recently shared some encouraging news on The Stem Cellar about a CIRM-funded stem cell clinical trial for spina bifida at UC … Continue reading CIRM-funding supports world’s first stem cell treatment for spina bifida delivered during fetal surgery

Stem Cell Agency Invests $46 Million in New Education Program

CIRM Bridges students 2022. The CIRM Board approved funding for a program to help even more students advance a career in science. The governing Board of the California Institute for Regenerative Medicine (CIRM) has approved $46,076,430 to invest in its newest education pillar- the COMPASS (Creating Opportunities through Mentorship and Partnership Across Stem cell Science) … Continue reading Stem Cell Agency Invests $46 Million in New Education Program

Life lessons learned in the CIRM summer intern program

SPARK poster session; Photo by Esteban Cortez When I was in high school I spent my summers working in a shoe shop and playing soccer with my mates. It never occurred to me that I could do something really  worthwhile with that time. So, when I meet the high school students who took part in … Continue reading Life lessons learned in the CIRM summer intern program