Dr. Judy Shizuru: Photo courtesy Jasper Therapeutics Over the years, the California Institute for Regenerative Medicine (CIRM) has invested a lot in helping children born with severe combined immunodeficiency (SCID), a fatal immune disorder. And we have seen great results, with some researchers reporting a 95 percent success rate in curing these children. SCID therapy … Continue reading Clinical trial for SCID
Bone marrow transplant
Man with HIV in remission after blood stem cell transplant
News that a stem cell transplant at City of Hope helped a man with HIV achieve long‑term remission made headlines worldwide—and rightly so. It’s a major achievement, especially because the 66‑year‑old patient had lived with HIV since 1988. What wasn’t highlighted is that the California Institute for Regenerative Medicine supported the work that made this … Continue reading Man with HIV in remission after blood stem cell transplant
Stem Cell Agency Board Invests in 19 Discovery Research Programs Targeting Cancers, Heart Disease and Other Disorders
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Judy Shizuru, Stanford University While stem cell and gene therapy research has advanced dramatically in recent years, there are still many unknowns and many questions remaining about how best to use these approaches in developing therapies. That’s why the governing Board of the California Institute … Continue reading Stem Cell Agency Board Invests in 19 Discovery Research Programs Targeting Cancers, Heart Disease and Other Disorders
Two reasons to remember June 19th
Today marks two significant events for the Black community. June 19th is celebrated as Juneteenth, the day when federal troops arrived in Galveston, Texas to ensure that the enslaved people there were free. That moment came two and a half years after President Abraham Lincoln signed the Emancipation Proclamation into law. June 19th is also … Continue reading Two reasons to remember June 19th
A new approach to a deadly childhood cancer
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Cancers of the blood, bone marrow and lymph nodes (also called hematologic malignancies) are the most common form of cancer in children and young adults. Current treatments can be effective but can also pose life-threatening health risks to the child. Now researchers at Stanford have developed … Continue reading A new approach to a deadly childhood cancer
Study shows reduction in brain injury after stroke patients were treated with their own stem cells
Illustration showing the mechanism of an ischemic stroke. In an ischemic stroke, blood supply to part of the brain is decreased, leading to dysfunction of that area of the brain. Here, a blood clot is the reason for restricted blood flow. Stroke is the third leading cause of death and serious long-term disability and affects … Continue reading Study shows reduction in brain injury after stroke patients were treated with their own stem cells
Surviving with Joy
Dr. Tippi MacKenzie (left) of UCSF Benioff Children’s Hospital San Francisco, visits with newborn Elianna and parents Nichelle Obar and Chris Constantino. Photo by Noah Berger Alpha thalassemia major is, by any stretch of the imagination, a dreadful, heart breaker of a disease. It's caused by four missing or mutated genes and it almost always … Continue reading Surviving with Joy
Overcoming obstacles in blood stem cell therapies
Photo Credit: OHSU Knight Cancer Institute Today, we here at CIRM wanted to provide an update on the fascinating world of hematopoietic (blood) stem cell-based therapies. What is the current status of this promising field and what are some of the challenges that need to be overcome? Dr. Kelly Shepard, Associate Director of Discovery and … Continue reading Overcoming obstacles in blood stem cell therapies
Capturing an image of blood stem cells
Image of a blood stem cell in its natural environment: Photo courtesy UC Merced UC Merced’s Professor Joel Spencer and his team developed a way of capturing an image of blood stem cells or image of blood stem cells inside their niche in the bone marrow. “Everyone knew black holes existed, but it took until … Continue reading Capturing an image of blood stem cells
Facebook Live: Ask the Stem Cell Team
On December 12th we hosted our latest 'Facebook Live: Ask the Stem Cell Team' event. We got a lot of questions and didn't have enough time to address them all. So here's answers to all the questions. What are the obstacles to using partial cellular reprogramming to return people’s entire bodies to a youthful state? … Continue reading Facebook Live: Ask the Stem Cell Team