In California, 690,000 people aged 65 and older are living with Alzheimer’s, a degenerative brain disease and the most common form of dementia. In the United States, 5.8 million people aged 65 and older live with Alzheimer's disease. Alzheimer's affects memory, thinking and behavior and symptoms eventually grow in severity to interfere with daily tasks. … Continue reading Study reveals new evidence of key mechanism in Alzheimer’s
Brain
“Brains” in a dish that can create electrical impulses
Brain organoids in a petri dish: photo courtesy UCSD For several years, researchers have been able to take stem cells and use them to make three dimensional structures called organoids. These are a kind of mini organ that scientists can then use to study what happens in the real thing. For example, creating kidney organoids … Continue reading “Brains” in a dish that can create electrical impulses
Salk scientists discover new findings related to the age of organs
Dr. Rafael Arrojo e Drigo (left) and Dr. Martin Hetzer (right) at the Salk Institute in San Diego It has been a long held belief in the scientific community that nerve cells, or possibly the heart, are the oldest cells in the body. This is due to the fact that the brain and heart are … Continue reading Salk scientists discover new findings related to the age of organs
Why having a wrinkled brain is a good thing
We normally associate wrinkles with aging, such as wrinkled skin. But there’s one organ that is wrinkled right from the time we are born. It’s our brain. And new research shows those wrinkles are not a sign of age but are, in fact, a sign of just how large and complex our brains are. The … Continue reading Why having a wrinkled brain is a good thing
Stem Cell Roundup: watching brain cells in real time, building better heart cells, and the plot thickens on the adult neurogenesis debate
Here are the stem cell stories that caught our eye this week. Watching brain cells in real time Our stem cell photo of the week is brought to you by the Khakh lab at UCLA Health. The lab developed a new method that allows scientists to watch brain cells interact in real time. Using a … Continue reading Stem Cell Roundup: watching brain cells in real time, building better heart cells, and the plot thickens on the adult neurogenesis debate
Stanford Scientist Sergiu Pasca Receives Prestigious Vilcek Prize for Stem Cell Research on Neuropsychiatric Disorders
Last month, we blogged about Stanford neuroscientist Sergiu Pasca and his interesting research using stem cells to model the human brain in 3D. This month we bring you an exciting update about Dr. Pasca and his work. On February 1st, Pasca was awarded one of the 2018 Vilcek Prizes for Creative Promise in Biomedical Science. … Continue reading Stanford Scientist Sergiu Pasca Receives Prestigious Vilcek Prize for Stem Cell Research on Neuropsychiatric Disorders
Modeling the Human Brain in 3D
Can you guess what the tiny white balls are in this photo? I’ll give you a hint, they represent the organ that you’re using right now to answer my question. These are 3D brain organoids generated from human pluripotent stem cells growing in a culture dish. You can think of them as miniature models of … Continue reading Modeling the Human Brain in 3D
Stem cell stories that caught our eye: brains, brains and more brains!
This week we bring you three separate stories about the brain. Two are exciting new advances that use stem cells to understand the brain and the third is plain creepy. Bioengineering better brains. Lab grown mini-brains got an upgrade thanks to a study published this week in Nature Biotechnology. Mini-brains are tiny 3D organs that … Continue reading Stem cell stories that caught our eye: brains, brains and more brains!
Rhythmic brain circuits built from stem cells
The TV commercial is nearly 20 years old but I remember it vividly: a couple is driving down a street when they suddenly realize the music on their tape deck is in sync with the repetitive activity on the street. From the guy casually dribbling a basketball to people walking along the sidewalk to the … Continue reading Rhythmic brain circuits built from stem cells
Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell transplants help put MS in remission: A combination of high dose immunosuppressive therapy and transplant of a person’s own blood stem cells seems to be a powerful tool in helping people with relapsing-remitting multiple sclerosis (RRMS) go into sustained remission. Multiple sclerosis (MS) is an autoimmune disorder where the body’s own immune system … Continue reading Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about