The Zika virus scare came to a head in 2015, prompting the World Health Organization to declare the outbreak a global health emergency earlier this year. From a research standpoint, much of the effort has centered on understanding whether the Zika infection is actually a cause of birth defects like microcephaly and how the virus … Continue reading UCSF Scientists find molecular link between brain stem cells and Zika Infection
Brain
Unlocking the brain’s secrets: scientists find over 100 unique mutations in brain cells
Your brain is made up of approximately 100 billion neurons. These are the cells that process information and pass along electrical and chemical signals to their other neuron buddies throughout the body to coordinate thoughts, movement, and many other functions. It’s no small task to create the intricate neuronal network that is the backbone of … Continue reading Unlocking the brain’s secrets: scientists find over 100 unique mutations in brain cells
CREATE-ing tools that deliver genes past the blood-brain barrier
Your brain has a natural defense that protects it from infection and harm, it’s called the blood-brain barrier (BBB). The BBB is a selectively permeable layer of tightly packed cells that separates the blood in your circulatory system from your brain. Only certain nutrients, hormones, and molecules can pass through the BBB into the brain, … Continue reading CREATE-ing tools that deliver genes past the blood-brain barrier
Four Challenges to Making the Best Stem Cell Models for Brain Diseases
Neurological diseases are complicated. A single genetic mutation causes some, while multiple genetic and environmental factors cause others. Also, within a single neurological disease, patients can experience varying symptoms and degrees of disease severity. And you can’t just open up the brain and poke around to see what’s causing the problem in living patients. It’s … Continue reading Four Challenges to Making the Best Stem Cell Models for Brain Diseases
Skipping a Step: Turning Brain Cells Directly into Neurons
It was once commonly believed that “what you see is what you get” with the human brain. As in, the brains cells that you are born with are the only ones you’ll have for the rest of your life because they can’t regenerate. The discovery of brain stem cells in the late 90s disproved this … Continue reading Skipping a Step: Turning Brain Cells Directly into Neurons
How Brain Stem Cells Could Stay Forever Young
As we age, so do the cells that make up our bodies. To keep us spry as we get older, our bodies rely on adult stem cells to replace the cells in our tissues and organs. Adult stem cells can only generate cell types specific to the organ or tissue that they live in. For … Continue reading How Brain Stem Cells Could Stay Forever Young
Stem cell stories that caught our eye: diabetes drug hits cancer, video stem cell tracker and quick n’ easy stem cells for fatal lung disease
Teaching an old drug new tricks. One the quickest way to get a drug to market is to find one that’s already been FDA approved for other diseases. Reporting this week in Cell Metabolism, researchers from London and Madrid identified the mechanisms that enable the anti-diabetic drug, metformin, to kill pancreatic cancer stem cells (PanCSCs). … Continue reading Stem cell stories that caught our eye: diabetes drug hits cancer, video stem cell tracker and quick n’ easy stem cells for fatal lung disease
Brain’s Own Activity Can Fuel Growth of Deadly Brain Tumors, CIRM-Funded Study Finds
Not all brain tumors behave alike. Some are much deadlier than others. High-grade gliomas, or HGGs, rank among the deadliest brain tumors. HGGs cause more brain tumor deaths than any other type in children and adults. Despite major advances in cancer research, survival rates for HGG patients have not improved. However, Stanford University researchers may … Continue reading Brain’s Own Activity Can Fuel Growth of Deadly Brain Tumors, CIRM-Funded Study Finds
Peering inside the brain: how stem cells could help turn skin into therapies for dementia
To truly understand a disease you need to be able to see how it works, how it causes our body to act in ways that it shouldn’t. In cancer, for example, you can take cells from a tumor and observe them under a microscope to see what is going on. But with diseases of the … Continue reading Peering inside the brain: how stem cells could help turn skin into therapies for dementia
Cranking it Up to Eleven: Heightened Growth of Neural Stem Cells Linked to Autism-like Behavior
Autism is not one single disease but a suite of many, which is why researchers have long struggled to understand its underlying causes. Often referred to as the Autism Spectrum Disorders, autism has been linked to multiple genetic and environmental factors—different combinations of which can all result in autism or autistic-like behavior. But as we … Continue reading Cranking it Up to Eleven: Heightened Growth of Neural Stem Cells Linked to Autism-like Behavior