When Alameda-based biotech company and CIRM awardee Scribe Therapeutics raised over $155 million from a recent IPO, it became the latest in a series of companies developing CIRM-supported therapies that have gone public or netted significant follow-on funding and investment. That’s good news for Californians whose tax dollars support the companies’ work. While biotech IPOs … Continue reading Another proof point from CIRM-supported research
Image Credit: The Adler Lab at the University of California, San Diego In the fall of 2024, the California Institute for Regenerative Medicine (CIRM) helped sponsor the Gene Therapy Initiative symposium in La Jolla, CA. While there, CIRM staff caught up with a few CIRM grantees who are working on gene therapy approaches to treating … Continue reading Gene Therapy for Heart Failure: A Conversation with Eric Adler, MD
Histology of human cardiac muscle under microscope. Credit: Shutterstock The California Institute for Regenerative Medicine (CIRM) recently announced funding a series of projects spanning the earliest stages of research through to clinical trials. A rare heart condition One of those projects was an $8 million award to Matthew Pollman, MD, MS, Senior Vice President of … Continue reading Advancing Heart Health: CIRM Funds Tenaya Therapeutics’ Gene Therapy Trial for ARVC
ENPP1 is expressed in the region of scarring after injury to the heart. Cardiac muscle shown in red and ENPP1 in green demonstrates expression of ENPP1 in the region of scar formation. | Credit: Arjun Deb Lab/UCLA At the California Institute for Regenerative Medicine (CIRM), we support cardiovascular research from Discovery through Clinical to advance … Continue reading UCLA researchers exploring ways to prevent heart failure after heart attacks
Arjun Deb, MD, a UCLA professor of medicine and biology, received a $6 million award from CIRM to advance his research on heart attack and heart failure treatments. Cardiovascular disease is the leading global cause of death, responsible for about one-third of all deaths. A heart attack causes permanent heart muscle damage and often leads … Continue reading CIRM awards $6 million to advance research for heart attack and heart failure treatments
Despite advances in treatments in recent years heart disease remains the leading cause of death in the US. One in three It accounts for one in three deaths in this country, and many people are not even aware they have a problem until they have a heart attack. One of the early warning signs of … Continue reading Using stem cells and smart machines to warn of heart problems
Smoking medical marijuana: Photo courtesy Elsa Olofsson Millions of Americans use marijuana for medical reasons, including easing anxiety or reducing side effects of cancer treatment. Millions more use it recreationally, saying it helps them relax. A new study now reports that regular marijuana smokers may increase their risk of heart disease and heart attack. Benefits … Continue reading Smoking marijuana could be bad for your heart, but there is an unusual remedy
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Darryl D'Lima: Scripps Health Every year millions of Americans suffer damage to their cartilage, either in their knee or other joints, that can eventually lead to osteoarthritis, pain and immobility. Today the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two projects targeting … Continue reading Two Early-Stage Research Programs Targeting Cartilage Damage Get Funding from Stem Cell Agency
Dr. Nicole Koutsodendris, photo courtesy Gladstone Institutes In the world of scientific research, the people doing clinical trials tend to suck up all the oxygen in the room. They’re the stars, the ones who are bringing potential therapies to patients. However, there’s another group of researchers who toil away in the background, but who are … Continue reading How some brilliant research may have uncovered a potential Alzheimer’s therapy
Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014 Dilated cardiomyopathy (DCM), a condition where the muscles of the heart are weak and can lead to heart failure, is considered rare in children. However, because the symptoms are not always easy to recognize the condition can go unnoticed for many years, and in severe cases … Continue reading Stem cell therapy may help mend a broken heart