Image Credit: University of Southern California (USC) Eye Institute Over the last two decades CIRM has supported research and helped advance potential treatments for macular degeneration, one of the leading causes of blindness. Early grants One of the earliest was a 2007 SEED grant to David Hinton, MD, of the University of Southern California (USC). … Continue reading The evolution of a CIRM-funded therapy for macular degeneration
Vision loss
CIRM invests $50 million in clinical research, including trial for vision loss
The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, today awarded $50.1 million to fund clinical-stage research projects aimed at advancing stem cell and gene therapy treatments for a variety conditions ranging from neurodegenerative diseases and blood cancers to HIV/AIDS. The awards will support six projects in the Agency’s … Continue reading CIRM invests $50 million in clinical research, including trial for vision loss
Lab-made retinas offer a new approach to battling vision loss
Age-related macular degeneration (AMD) is the leading cause of vision loss in the elderly. Now, new research using 3D organoid models of the eye has uncovered clues as to what happens in AMD, and how to stop it. In AMD, a person loses their central vision because the light sensitive cells in the macula, a … Continue reading Lab-made retinas offer a new approach to battling vision loss
Stem cells help researchers map out glaucoma in search for new treatments
Glaucoma is the world’s leading cause of irreversible blindness. There is no cure and current treatments are only able to slow down the progression of the disease. Now research using stem cells to create a genetic blueprint of glaucoma is giving scientist a powerful new tool to combat the disease. Glaucoma occurs when healthy retinal … Continue reading Stem cells help researchers map out glaucoma in search for new treatments
Study shows sleep deprivation impairs stem cells in the cornea
We spend around one third of our life sleeping—or at least we should. Not getting enough sleep can have serious consequences on many aspects of our health and has been linked to high blood pressure, heart disease and stroke. A study by the American Sleep Apnea Association found that some 70 percent of Americans report getting … Continue reading Study shows sleep deprivation impairs stem cells in the cornea
How a tiny patch is helping restore lasting vision
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Researchers are working on a stem cell-based retinal implant that could be used for people with with advanced dry age-related macular degeneration. (Photo/ Britney O. Pennington) When Anna Kuehl began losing her vision, she feared losing the ability to read and go on long walks in … Continue reading How a tiny patch is helping restore lasting vision
Reprogramming brain cells to restore vision after a stroke
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST About one third of stroke survivors experience vision loss. It can be a devastating side effect as most patients will not fully recover their vision and there are currently no reliable treatments available. But thanks to a collaborative effort by two teams of researchers from Purdue … Continue reading Reprogramming brain cells to restore vision after a stroke
National Academy of Medicine honors CIRM Grantees
YOU CAN ALSO LISTEN TO THIS BLOG AS AN AUDIO PODCAST ON SPOTIFY As someone who is not always as diligent as he would like to be about sending birthday cards on time, I’m used to sending belated greetings to people. So, I have no shame in sending belated greetings to four CIRM grantees who … Continue reading National Academy of Medicine honors CIRM Grantees
Sometimes a cold stare is a good thing
A retina of a patient with macular degeneration. (Photo credit: Paul Parker/SPL) Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in the elderly in the U.S. It’s estimated that some 11 million Americans could have some form of the disease, a number that is growing every year. So if you … Continue reading Sometimes a cold stare is a good thing
Two voices, one message, watch out for predatory stem cell clinics
Last week two new papers came out echoing each other about the dangers of bogus “therapies” being offered by predatory stem cell clinics and the risks they pose to patients. The first was from the Pew Charitable Trusts entitled: ‘Harms Linked to Unapproved Stem Cell Interventions Highlight Need for Greater FDA Enforcement’ with a subtitle: … Continue reading Two voices, one message, watch out for predatory stem cell clinics