Dr. Tariq Rana (left) and Dr. Jeremy Rich (right) both lead independent teams at UC San Diego that identified a molecule, αvβ5 integrin, as the Zika virus' key to getting into brain stem cells Zika virus is caused by a virus transmitted by Aedes mosquitoes. People usually develop mild symptoms that include fever, rash, and … Continue reading Two studies identify a molecule that could be used to block Zika virus and kill cancer cells
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USC study shows how tumor cells in the bloodstream can target distant organs
Various types of cancer can become particularly aggressive and difficult to treat once they spread from their initial point of origin to other parts of the body. This unfortunate phenomenon, known as metastasis, can make treatment very challenging, decreasing the chance of survival for the patient. In order to better understand this process, a CIRM … Continue reading USC study shows how tumor cells in the bloodstream can target distant organs
New model unlocks clues to treat a deadly childhood cancer
CIRM-funded research at Sanford Burnham Prebys Medical Discovery Institute in San Diego is identifying compounds that could be clues to treat a deadly childhood cancer. A rare brain cancer The cancer is choroid plexus carcinoma (CPC), a rare brain tumor that occurs mainly in children. As it grows the tumor can affect nearby parts of … Continue reading New model unlocks clues to treat a deadly childhood cancer
Antibody effective in cure for rare blood disorders
3D illustration of an antibody binding to a designated target. Illustration created by Audra Geras. A variety of diseases can be traced to a simple root cause: problems in the bone marrow. The bone marrow contains specialized stem cells known as hematopoietic stem cells (HSCs) that give rise to different types of blood cells. As … Continue reading Antibody effective in cure for rare blood disorders
Tips on how to be a great Patient Advocate from three of the best Advocates around
No one sets out to be a Patient Advocate. It’s something that you become because of something that happens to you. Usually it’s because you, or a loved one or a friend, becomes ill and you want to help find a treatment. Whatever the reason, it is the start of a journey that often throws … Continue reading Tips on how to be a great Patient Advocate from three of the best Advocates around
Targeted treatment for pediatric brain tumors shows promising results
Image of medulloblastoma Imagine sitting in the doctor's office and being told the heartbreaking news that your child has been diagnosed with a malignant brain tumor. As one might expect, the doctor states that the most effective treatment option is typically a combination of chemotherapy and radiation. However, the doctor reveals that there are additional … Continue reading Targeted treatment for pediatric brain tumors shows promising results
Signal in Cancer Cells Points to New Immunotherapies
People usually think of the immune system when they talk about colds or flu. Immune cells do fight viruses and bacteria, but they also destroy abnormal cancer cells inside the body. “Don’t Eat Me” Signal 101 A white blood cell called a macrophage is part of the innate immune system. It patrols tissues and engulfs … Continue reading Signal in Cancer Cells Points to New Immunotherapies
Achilles’ Heel of Brain Cancer Identified in Tumor Stem Cells
Few words strike me with more dread than glioblastoma, the name for a very aggressive, incurable cancer of the brain. Although surgery and chemotherapy can help hold off or reverse a glioblastoma’s growth for a while, almost inevitably the tumor comes back along with a terrible prognosis: an average survival time of 12 to 15 … Continue reading Achilles’ Heel of Brain Cancer Identified in Tumor Stem Cells
New developments in prostate cancer from UCLA
Today we’re bringing you a research update from a CIRM-funded team at UCLA that’s dedicated to finding a cure for prostate cancer. The team is led by Dr. Owen Witte, the director of the UCLA Broad Stem Cell Research Center and a Howard Hughes Investigator. Dr. Witte is well known for his work in leukemia … Continue reading New developments in prostate cancer from UCLA
Scientists use human stem cell models to target deadly brain cancer
Malignant brain cancer is a devastating disease and it’s estimated that more than 16,000 patients will die of it this year. One of the most aggressive forms of brain cancer is gliomas, which originate from the support cells in the brain or spine that keep nerve cells happy and functioning. Unfortunately, there is no cure … Continue reading Scientists use human stem cell models to target deadly brain cancer