Holding a curved device that looked a bit like a mariner’s sextant, neurosurgeon Warren Boling explained how he’ll use it to precisely deliver a new gene therapy deep into the brains of Parkinson's patients participating in a pivotal clinical trial. A colony of iPSCs from a Parkinson's patient (left) and dopaminergic neurons made from these … Continue reading Three CIRM-funded approaches advance potential Parkinson’s treatments
From the age of three, Tara Radcliffe Ghiglieri danced almost every day, leaping, pirouetting, tapping, and high kicking her way into a Broadway career that included a multi-year stint as a Radio City Rockette. She trained hard, at times rehearsing eight hours a day, six days a week. "And performance days could be up to … Continue reading Experimental treatment brings relief for a dancer with chronic knee pain
By Holly Alyssa MacCormick A single infusion of a modified CAR-T cell therapy could pave the way for a potential one-shot cure for HIV, according to preliminary findings of a small, early-stage clinical trial. Steven G. Deeks, MD, the principal investigator of this California Institute for Regenerative Medicine (CIRM)-funded clinical trial, discussed the findings at a recent CIRM board meeting. Steven Deeks, MD Photo: UCSF Roughly 40 million people worldwide and more … Continue reading Early trial shows promise for one‑shot cure for HIV
Knee joint pain rarely gets counted among major public‑health burdens. Yet it affects more than 3 million Californians and 34 million people across the U.S., with both massive economic and health consequences. Costly Impact In California alone, the cost of knee replacement surgeries exceeds $8 billion annually, according to Thomas Chalberg, PhD, founder and CEO … Continue reading Genascence discusses gene therapy for knee osteoarthritis