Every year, California performs around 100 kidney transplants in children, but, on average, around 50 of these patients will have their bodies reject the transplant. Improving kidney transplant outcomes These children then have to undergo regular dialysis while waiting for a new organ. Even the successful transplants require a lifetime of immunosuppression medications. These medications … Continue reading Making kidney transplants easier for kids and charting a new approach to fighting solid tumors.
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Lack of diversity impacts research into Alzheimer’s and dementia
THIS BLOT IS ALSO AVAILABLE AS AN AUDIOCAST ON SPOTIFY A National Institutes of Allergy and Infectious Diseases clinical trial admissions coordinator collects information from a volunteer to create a medical record. Credit: NIAID Alzheimer’s research has been in the news a lot lately, and not for the right reasons. The controversial decision by the … Continue reading Lack of diversity impacts research into Alzheimer’s and dementia
How regrowing tiny hairs could restore hearing loss
Man getting fitted with hearing aids Hearing loss is something that affect tens of millions of Americans. Usually people notice those changes as they get older but the damage can be done years before that through the use of some prescription drugs or exposure to loud noise (I knew I shouldn’t have sat in the … Continue reading How regrowing tiny hairs could restore hearing loss
Medeor Therapeutics Completes Enrollment in CIRM-Funded Clinical Trial for Kidney Transplant Patients
A CIRM-funded clinical trial to help kidney transplant patients avoid the need for anti-rejection or immunosuppressive medications has completed enrollment and transplantation of all patients. Medeor Therapeutics’ MDR-101 Phase 3 multi-center clinical trial involved 30 patients; 20 of them were treated with MDR-101, and 10 control subjects were given standard care. CIRM awarded Medeor, based … Continue reading Medeor Therapeutics Completes Enrollment in CIRM-Funded Clinical Trial for Kidney Transplant Patients
CIRM-funded kidney transplant procedure progresses
Kidney transplant surgery. Medeor Therapeutics, which is running a CIRM-funded clinical trial to help people getting kidney transplants, just got some really good news. The US Food and Drug Administration (FDA) has just granted their product Regenerative Medicine Advanced Therapy (RMAT) designation. That’s a big deal because it may allow them to apply for faster … Continue reading CIRM-funded kidney transplant procedure progresses
Two rare diseases, two pieces of good news
Dr. Stephanie Cherqui Last week saw a flurry of really encouraging reports from projects that CIRM has supported. We blogged about two of them last Wednesday, but here’s another two programs showing promising results. UC San Diego researcher Dr. Stephanie Cherqui is running a CIRM-funded clinical trial for cystinosis. This is a condition where patients … Continue reading Two rare diseases, two pieces of good news
Huge honor, hugely deserved for CIRM-funded stem cell researcher
Dr. Andy McMahon: Photo courtesy USC Andy McMahon is one of the most understated, humble and low-key people you are ever likely to meet. He’s also one of the smartest. And he has a collection of titles to prove it. He is the W.M. Keck Provost and University Professor in USC’s departments of Stem Cell … Continue reading Huge honor, hugely deserved for CIRM-funded stem cell researcher
Donor blood stem cells and T cells could help patients wean off immunosuppressive drugs after organ transplant
Dr. Samuel Strober is refining a process that eliminates the need for the many immunosuppresant drugs normally required after a transplant.Image credit: Stanford Medicine News Center In 2019, there were over 23,000 kidney transplants in the United States, according to figures from the United Network for Organ Sharing (UNOS). These transplants can be lifesaving, but … Continue reading Donor blood stem cells and T cells could help patients wean off immunosuppressive drugs after organ transplant
The Most Important Gift of All
Photo courtesy American Hospital Association There are many players who have a key role in helping make a stem cell therapy work. The scientists who develop the therapy, the medical team who deliver it and funders like CIRM who provide the money to make this all happen. But vital as they are, in some therapies … Continue reading The Most Important Gift of All
Rare Disease Gets Big Boost from California’s Stem Cell Agency
UC Irvine's Dr. Leslie Thompson and patient advocate Frances Saldana after the CIRM Board vote to approve funding for Huntington's disease If you were looking for a poster child for an unmet medical need Huntington’s disease (HD) would be high on the list. It’s a devastating disease that attacks the brain, steadily destroying the ability … Continue reading Rare Disease Gets Big Boost from California’s Stem Cell Agency