A colony of iPSCs from a Parkinson's patient (left) and dopaminergic neurons made from these iPSCs (right) to model PD. (Image credit: Jeanne Loring) A new study that used adult blood stem cells to create replacement brain nerve cells appears to help rats with Parkinson’s. In Parkinson’s, the disease attacks brain nerve cells that produce … Continue reading Replacement brain cells offer hope for Parkinson’s treatment
regenerative medicine
UCLA-led team creates first comprehensive map of human blood stem cell development
Human blood stem cells emerging from specialized endothelial cells in the wall of an embryonic aorta. UCLA scientists’ confirmation of this process clarifies a longstanding controversy about the stem cells’ cellular origin. Image Credit: Hanna Mikkola Lab/UCLA, Katja Schenke-Layland Lab/University of Tübingen, Nature California researchers at UCLA and colleagues have created a first-of-its-kind roadmap that … Continue reading UCLA-led team creates first comprehensive map of human blood stem cell development
Next-generation regenerative science workforce
Bridges scholars presenting their research posters to CIRM team members and other scientists Regenerative medicine is a diverse, rapidly evolving field that draws on expertise from biologists, engineers, and clinicians. Building a skilled workforce As the field advances, it needs a highly trained workforce to translate discoveries into patient care. That’s why a key goal … Continue reading Next-generation regenerative science workforce
CIRM scholars growing the regenerative medicine field in California
CIRM Scholar Alessandra Rodriguez y Baena CIRM scholar Alessandra’s story illustrates just one of the many ways CIRM has helped nurture the future of regenerative medicine in California. Gaining Exposure to Innovative Research CIRM Scholar Alessandra Rodriguez y Baena was a Master’s student at Cal Poly, San Luis Obispo. With the support of CIRM’s Bridges Program, she became a CIRM intern in the Willert Lab … Continue reading CIRM scholars growing the regenerative medicine field in California
Feds hit predatory stem cell clinics with a one-two punch
Federal Trade Commission Stem cells have a number of amazing properties and tremendous potential to heal previously untreatable conditions. But they also have the potential to create a financial windfall for clinics that are more focused on lining their wallets than helping patients. Now the federal government is cracking down on some of these clinics … Continue reading Feds hit predatory stem cell clinics with a one-two punch
Sometimes a cold stare is a good thing
A retina of a patient with macular degeneration. (Photo credit: Paul Parker/SPL) Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in the elderly in the U.S. It’s estimated that some 11 million Americans could have some form of the disease, a number that is growing every year. So if you … Continue reading Sometimes a cold stare is a good thing
New Study Shows CIRM-Supported Therapy Cures More than 95% of Children Born with a Fatal Immune Disorder
Dr. Donald B. Kohn; Photo courtesy UCLA A study published in the New England Journal of Medicine shows that an experimental form of stem cell and gene therapy has cured 48 of 50 children born with a deadly condition called ADA-SCID. Children with ADA-SCID, (severe combined immunodeficiency due to adenosine deaminase deficiency) lack a key … Continue reading New Study Shows CIRM-Supported Therapy Cures More than 95% of Children Born with a Fatal Immune Disorder
Remembering Eli Broad, philanthropist and stem cell champion
Eli Broad, Photo by Nancy Pastor The world of stem cell research lost a good friend this weekend. Eli Broad, a generous supporter of science, education and the arts, passed away at the age of 87. Eli came from humble origins, born in the Bronx to an immigrant father who worked as a house painter … Continue reading Remembering Eli Broad, philanthropist and stem cell champion
Women who have changed, and are changing, the world
The problem with trying to write about something like Women’s History Month is where do you start? Even if you narrow it down to women in science the list is vast. Marie Curie I suppose you could always start with Maria Salomea Skłodowska who is better known as Marie Curie. She not only discovered radium … Continue reading Women who have changed, and are changing, the world
Building a gene and cell therapy pipeline
Dr. Kelly Shepard By Dr. Kelly Shepard We love sharing exciting news about recent discoveries or announcing the launch of a new CIRM-funded clinical trial because they offer tangible signs of progress, but the background work to build a gene and cell therapy "pipeline" is no less important. Behind the scenes Important signs of progress also happen … Continue reading Building a gene and cell therapy pipeline