Stem cell stories that caught our eye: heart muscle-on-a-chip, your own private microliver, the bloody holy grail and selfish sperm

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Two hearts beat as one, or not Sorry for the pre-Valentine’s Day buzzkill but stem cell research published this past week points to a very … Continue reading Stem cell stories that caught our eye: heart muscle-on-a-chip, your own private microliver, the bloody holy grail and selfish sperm

A cardiac love triangle: how transcription factors interact to make a heart

 Here’s a heartfelt science story for all those Valentine’s day fans out there. Scientists from the Gladstone Institutes have identified how a group of transcription factors interact during embryonic development to make a healthy heart. Their work will increase our biological understanding of how the heart is formed and could produce new methods for treating … Continue reading A cardiac love triangle: how transcription factors interact to make a heart

CIRM Scholar Jessica Gluck on using stem cells to make biological pacemakers for the heart

As part of our CIRM scholar series, we feature the research accomplishments of students and postdocs that have received CIRM funding. I’d like to introduce you to one of our CIRM Scholars, Jessica Gluck. She’s currently a Postdoctoral Fellow at UC Davis working on human stem cell models of heart development. Jessica began her education … Continue reading CIRM Scholar Jessica Gluck on using stem cells to make biological pacemakers for the heart

Timing is everything: could CRISPR gene editing push CIRM to change its rules on funding stem cell research?

Talk about timely. When we decided, several months ago, to hold a Standards Working Group (SWG) meeting to talk about the impact of CRISPR, a tool that is transforming the field of human gene editing, we had no idea that our meeting would fall smack in the midst of a flurry of news stories about … Continue reading Timing is everything: could CRISPR gene editing push CIRM to change its rules on funding stem cell research?

How you derive embryonic stem cells matters

A scientist named James Thompson was the first to successfully culture human embryonic stem cells in 1998. He didn’t know it then, but his technique isolated a specific type of embryonic stem cell (ESC) that had a “primed pluripotent state”. There are actually two phases of pluripotency: naïve and primed. Naïve ESCs occur a step … Continue reading How you derive embryonic stem cells matters

Stem cell stories that caught our eye: affairs of the heart, better imaging of cells and pituitary glands in a dish

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Matters of the heart not simple. The dozens of clinical trials using various types of stem cells to repair hearts after a heart attack have … Continue reading Stem cell stories that caught our eye: affairs of the heart, better imaging of cells and pituitary glands in a dish

Sushi Just Got Even Better: Gel Made from Seaweed Improves the Shelf-Life of Stem Cells

The beauty of pharmaceutical drugs is their stability. Those ibuprofen pills in your medical cabinet can sit there for weeks, months, even years but still dull a sudden headache. Stem cell-based therapies don’t have that luxury because, well, they’re made of living cells. Outside of the body, cells are the opposite of stable. To keep … Continue reading Sushi Just Got Even Better: Gel Made from Seaweed Improves the Shelf-Life of Stem Cells

A Tale of Two Stem Cell Treatments for Growing New Bones

Got Milk? If you grew up during the 90’s, you most certainly will remember the famous “Got Milk?” advertising campaign to boost milk consumption. The plug was that milk was an invaluable source of calcium, a mineral that’s essential for growing strong bones. Drinking three glasses of the white stuff a day, supposedly would help … Continue reading A Tale of Two Stem Cell Treatments for Growing New Bones

If you want to accelerate stem cell therapies then create an Accelerating Center

“You can’t teach fish to fly,” is one of the phrases that our CIRM President & CEO, Randy Mills, likes to throw out when asked why we needed to create new centers to help researchers move their most promising therapies out of the lab and into clinical trials. His point is that many researchers are … Continue reading If you want to accelerate stem cell therapies then create an Accelerating Center

CREATE-ing tools that deliver genes past the blood-brain barrier

Your brain has a natural defense that protects it from infection and harm, it’s called the blood-brain barrier (BBB). The BBB is a selectively permeable layer of tightly packed cells that separates the blood in your circulatory system from your brain. Only certain nutrients, hormones, and molecules can pass through the BBB into the brain, … Continue reading CREATE-ing tools that deliver genes past the blood-brain barrier