Diseases of the brain have many different names, from Alzheimer’s and Parkinson’s to ALS and Huntington’s, but they often have similar causes. Researchers at the Gladstone Institutes in San Francisco are using that knowledge to try and find an approach that might be effective against all of these diseases. In a new CIRM-funded study, … Continue reading Using stem cells to fix bad behavior in the brain
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Measuring depression with non-invasive imaging of new brain cells
For most of the 20th century, scientists thought you’re basically stuck with the brain cells you’re born with. “Everything may die, nothing may be regenerated”, is how Santiago Ramón y Cajal, the father of modern neuroscience, described nerve cells, aka neurons, in the adult brain. But, over the past few decades, it’s become clear that … Continue reading Measuring depression with non-invasive imaging of new brain cells
Salk scientists explain why brain cells are genetically diverse
I’ve always wondered why some sets of genetically identical twins become not so identical later in life. Sometimes they differ in appearance. Other times, one twin is healthy while the other is plagued with a serious disease. These differences can be explained by exposure to different environmental factors over time, but there could also be … Continue reading Salk scientists explain why brain cells are genetically diverse
Stem cell transplant offers Jake a glimpse of hope
Jake Javier surrounded by friends; Photo courtesy Julie Haener KTVU On Thursday, July 7th, Jake Javier became the latest member of a very select group. Jake underwent a stem cell transplant for a spinal cord injury at Santa Clara Valley Medical Center here in the San Francisco Bay Area. The therapy is part of the … Continue reading Stem cell transplant offers Jake a glimpse of hope
Adding new stem cell tools to the Parkinson’s disease toolbox
Understanding a complicated neurodegenerative disorder like Parkinson’s disease (PD) is no easy task. While there are known genetic risk factors that cause PD, only about 10 percent of cases are linked to a genetic cause. The majority of patients suffer from the sporadic form of PD, where the causes are unknown but thought to be … Continue reading Adding new stem cell tools to the Parkinson’s disease toolbox
Approach that inspires DREADD could create new way to treat Parkinson’s disease
Dopamine producing brain nerve cells, made from embryonic stem cells Imagine having a treatment for Parkinson’s that acts like a light switch, enabling you to turn it on or off depending on your needs. Well, that’s what researchers at the University of Wisconsin-Madison have come up with. And if it works, it might help change … Continue reading Approach that inspires DREADD could create new way to treat Parkinson’s disease
An inside look reveals the adult brain prunes its own branches
Did you know that when you’re born, your brain contains around 100 billion nerve cells? This is impressive considering that these nerve cells, also called neurons, are already connected to each other through an intricate, complex neural network that is essential for brain function. Here’s how the brain does it. During development, neural stem cells … Continue reading An inside look reveals the adult brain prunes its own branches
Unlocking the brain’s secrets: scientists find over 100 unique mutations in brain cells
Your brain is made up of approximately 100 billion neurons. These are the cells that process information and pass along electrical and chemical signals to their other neuron buddies throughout the body to coordinate thoughts, movement, and many other functions. It’s no small task to create the intricate neuronal network that is the backbone of … Continue reading Unlocking the brain’s secrets: scientists find over 100 unique mutations in brain cells
Bringing down the gatekeeper for a stem cell-based Parkinson’s cure
On the surface, a stem cell-based cure for Parkinson’s disease seems pretty straight-forward. This age-related neurodegenerative disorder, which leads to progressively worsening tremors, slowness of movement and muscle rigidity, is caused by the death of a specific type of nerve cell, or neuron, that produces the chemical dopamine in a specific region of the brain. … Continue reading Bringing down the gatekeeper for a stem cell-based Parkinson’s cure
CIRM Scholar Spotlight: Berkeley’s Maroof Adil on stem cell transplants for Parkinson’s disease
Stem cell therapy has a lot of potential for Parkinson’s patients and the scientists that study it. One of our very own CIRM scholars, Maroof Adil, is making it his mission to develop stem cell based therapies to treat brain degenerating diseases like Parkinson’s. Maroof got his undergraduate degrees from MIT in both Chemical Engineering … Continue reading CIRM Scholar Spotlight: Berkeley’s Maroof Adil on stem cell transplants for Parkinson’s disease
The Stem Cellar 