A study by Stanford Medicine researchers in older mice may lead to treatments that help seniors regain muscle strength lost to aging. Muscle stem cells—which are activated in response to muscle injury to regenerate damaged muscle tissue—lose their potency with age. A study from the National Health and Nutrition Examination Survey showed that five percent … Continue reading Study could pave the way in reducing decline in muscle strength as people age
muscle stem cells
Repairing damaged muscles
Close-up of the arm of a 70-year-old male patient with a torn biceps muscle as a result of a bowling injury; Photo courtesy Science Photo Library In the time of coronavirus an awful lot of people are not just working from home they’re also working out at home. That’s a good thing; exercise is a … Continue reading Repairing damaged muscles
Stem Cell Agency Board Approves Three More Projects Targeting COVID-19
Dr. Jianhua Yu (left), Dr. Helen Blau (center), and Dr. Albert Wong (right) The COVID-19 virus targets many different parts of the body, often with deadly or life-threatening consequences. This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) approved investments in three early-stage research programs taking different approaches to battling … Continue reading Stem Cell Agency Board Approves Three More Projects Targeting COVID-19
Promising results from CIRM-funded projects
Severe Leukocyte Adhesion Deficiency-1 (LAD-1) is a rare condition that causes the immune system to malfunction and reduces its ability to fight off viruses and bacteria. Over time the repeated infections can take a heavy toll on the body and dramatically shorten a person’s life. But now a therapy, developed by Rocket Pharmaceuticals, is showing … Continue reading Promising results from CIRM-funded projects
From organs to muscle tissue: how stem cells are being used in 3D
A Sunday Afternoon on the Island of La Grande Jatte by Georges-Pierre Seurat When most people think of stem cells, they might conjure up an image of small dots under a microscope. It is hard to imagine these small specs being applied to three-dimensional structures. But like a pointillism painting, such as A Sunday Afternoon … Continue reading From organs to muscle tissue: how stem cells are being used in 3D
Muscle stem cells provide insight into treatment of muscular dystrophies and aging muscles
Dr. Alessandra Sacco, associate professor in the Development, Aging and Regeneration Program at Sanford Burnham Prebys. Muscles are a vital part of the body that enable us to walk, run, lift, and do everyday activities. When muscles start to deteriorate, we start to have difficulty performing these activities, which severely limits quality of life and … Continue reading Muscle stem cells provide insight into treatment of muscular dystrophies and aging muscles
An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration
We’ve written many blogs over the years about research focused on muscle stem cell function . Those stories describe how satellite cells, another name for muscle stem cells, lay dormant but jump into action to grow new muscle cells in response to injury and damage. And when satellite function breaks down with aging as well as … Continue reading An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration
Have scientists discovered a natural way to boost muscle regeneration?
Painkillers like ibuprofen and aspirin are often a part of an athlete’s post-exercise regimen after intense workouts. Sore muscles, aches and stiffness can be more manageable by taking these drugs – collectively called non-steroidal anti-inflammatory drugs, or NSAIDS – to reduce inflammation and pain. But research suggests that the anti-inflammatory effects of these painkillers might … Continue reading Have scientists discovered a natural way to boost muscle regeneration?
Scientists find new stem cell target for regenerating aging muscles
Today I’m going to use our former governor Arnold Schwarzenegger as an example of what happens to our muscles when we age. One of Arnold’s many talents when he was younger was being a professional bodybuilder. As you can see in this photo, Arnold worked hard to generate an impressive amount of muscle that landed … Continue reading Scientists find new stem cell target for regenerating aging muscles
Stem cell stories that caught our eye: sexual identity of organs, upping the game of muscle stem cells, mini guts produce insulin
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. A new sexual identity crisis—in our organs. With the transition from Mr. to Ms. Jenner and other transsexual news this year, it seems inevitable that … Continue reading Stem cell stories that caught our eye: sexual identity of organs, upping the game of muscle stem cells, mini guts produce insulin
The Stem Cellar 