Colorized scanning electron micrograph of a natural killer cell.Photo credit: National Institute of Allergy and Infectious Diseases Racing car drivers are forever tinkering with their cars, trying to streamline them and soup up their engines because while fast is good, faster is better. Researchers do the same things with potential anti-cancer therapies, tinkering with them … Continue reading Super charging killer cells to fight leukemia
iPSCs
You can bank on CIRM
Way back in 2013, the CIRM Board invested $32 million in a project to create an iPSC Bank. The goal was simple; to collect tissue samples from people who have different diseases, turn those samples into high quality stem cell lines - the kind known as induced pluripotent stem cells (iPSC) - and create a … Continue reading You can bank on CIRM
What to be thankful for this Thanksgiving: scientists hard at work
Biomedical technician Louis Pinedo feeds stem cells their special diet. Photo by Cedars-Sinai. With Thanksgiving and Black Friday approaching in the next couple of days, we wanted to give thanks to all the scientists hard at work during this holiday weekend. Science does not sleep--the groundbreaking research and experiments that are being conducted do not … Continue reading What to be thankful for this Thanksgiving: scientists hard at work
Blood-brain barrier chip created with stem cells expands potential for personalized medicine
An Organ-Chip used in the study to create a blood-brain barrier (BBB). The brain is a complex part of the human body that allows for the formation of thoughts and consciousness. In many ways it is the essence of who we are as individuals. Because of its importance, our bodies have developed various layers of … Continue reading Blood-brain barrier chip created with stem cells expands potential for personalized medicine
First patient treated for colon cancer using reprogrammed adult cells
Dr. Sandip Patel (left) and Dr. Dan Kaufman (center) of UC San Diego School of Medicine enjoy a light-hearted moment before Derek Ruff (right) receives the first treatment for cancer using human-induced pluripotent stem cells (hiPSCs). Photo courtesy of UC San Diego Health. For patients battling cancer for the first time, it can be quite … Continue reading First patient treated for colon cancer using reprogrammed adult cells
A new stem cell derived tool for studying brain diseases
Sergiu Pasca’s three-dimensional culture makes it possible to watch how three different brain-cell types – oligodendrocytes (green), neurons (magenta) and astrocytes (blue) – interact in a dish as they do in a developing human brain. Courtesy of the Pasca lab Neurological diseases are among the most daunting diagnoses for a patient to receive, because they … Continue reading A new stem cell derived tool for studying brain diseases
Midwest universities are making important tools to advance stem cell research
Two Midwest universities are making headlines for their contributions to stem cell research. Both are developing important tools to advance this field of study, but in two unique ways. Scientists at the University of Michigan (UM), have compiled an impressive repository of disease-specific stem cell lines. Cell lines are crucial tools for scientists to study … Continue reading Midwest universities are making important tools to advance stem cell research
Sequencing data helps us understand the genes involved in heart cell development
Heart disease is the leading cause of death for both men and women in the United States and is estimated to be responsible for 31% of all deaths globally. This disease encompasses a wide variety of conditions that all effect how well your heart is able to pump blood to the rest of your body. … Continue reading Sequencing data helps us understand the genes involved in heart cell development
Coming up with a stem cell FIX for a life-threatening blood disorder
A promising new treatment option for hemophiliacs is in the works at the Salk Institute for Biological Sciences. Patients with Hemophilia B experience uncontrolled, and sometimes life threatening, bleeding due to loss or improper function of Factor IX (FIX), a protein involved in blood clotting. There is no cure for the disease and patients rely … Continue reading Coming up with a stem cell FIX for a life-threatening blood disorder
Celebrating Exciting CIRM-Funded Discovery Research on World Parkinson’s Day
April 11th is World Parkinson’s Disease Awareness Day. To mark the occasion, we’re featuring the work of CIRM-funded researchers who are pursuing new, promising ideas to treat patients with this debilitating neurodegenerative disease. Birgitt Schuele, Parkinson’s Institute CIRM Grant: Quest Award – Discovery Stage Research Research: Birgitt and her team at the Parkinson’s Institute in … Continue reading Celebrating Exciting CIRM-Funded Discovery Research on World Parkinson’s Day
The Stem Cellar 