Gladstone researchers discovered a method to control the patterns stem cells form in a dish. The work was led by Senior Investigator Todd McDevitt (left) and his team, including (pictured) David Joy and Ashley Libby. When someone thinks of machine learning, the first thing that comes to mind might be the technology used by Netflix … Continue reading Machine learning used to pattern stem cells – a vital step in organ modeling
CRISPR
Stanford and University of Tokyo researchers crack the code for blood stem cells
Blood stem cells grown in lab Blood stem cells offer promise for a variety of immune and blood related disorders such as sickle cell disease and leukemia. Like other stem cells, blood stem cells have the ability to generate additional blood stem cells in a process called self-renewal. Additionally, they are able to generate blood … Continue reading Stanford and University of Tokyo researchers crack the code for blood stem cells
Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
Dr. Matthew Porteus, professor of pediatrics at Stanford University. Photo courtesy of Stanford Medicine. Our immune system is an important and essential part of everyday life. It is crucial for fighting off colds and, with the help of vaccinations, gives us immunity to potentially lethal diseases. Unfortunately, for some infants, this innate bodily defense mechanism … Continue reading Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Illustration courtesy of TED website There has been a lot of conversation surrounding CRISPR-Cas9 in these recent months as well as many sensational news stories. Some of these stories highlight the promise this technology holds, while others emphasize a word of caution. But what exactly does this technology do and how does it work? Here … Continue reading CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Researcher claims to have made first gene-edited baby. But did it really happen?
Remember the Raelians? Probably not. But way back in 2002 the group, some described them as a cult, claimed it had created the world’s first cloned baby. The news made headlines all around the world raising fears we were stepping into uncharted scientific territory. Several weeks later the scientist brought in by the Raelians to … Continue reading Researcher claims to have made first gene-edited baby. But did it really happen?
Has Regenerative Medicine Come of Age?
For the past few years the Signals blog site - which offers an insiders’ perspectives on the world of regenerative medicine and stem cell research - has hosted what it calls a "Blog Carnival". This is an event where bloggers from across the stem cell field are invited to submit a piece based on a … Continue reading Has Regenerative Medicine Come of Age?
For the first time, scientists entirely reprogram human skin cells to iPSCs using CRISPR
Back in 2012, Shinya Yamanaka was awarded the Nobel Prize in Physiology or Medicine for his group’s identification of “Yamanaka Factors,” a group of genes that are capable of turning ordinary skin cells into induced pluripotentent stem cells (iPSCs) which have the ability to become any type of cell within the body. Discovery of iPSCs … Continue reading For the first time, scientists entirely reprogram human skin cells to iPSCs using CRISPR
Stem Cell Roundup: New understanding of Huntington’s; how stem cells can double your DNA; and using “the Gary Oldman of cell types” to reverse aging
This week's roundup highlights how we are constantly finding out new and exciting ways that stem cells could help change the way we treat disease. Our Cool Stem Cell Image of the Week comes from our first story, about unlocking some of the secrets of Huntington's disease. It comes from the Laboratory of Stem Cell … Continue reading Stem Cell Roundup: New understanding of Huntington’s; how stem cells can double your DNA; and using “the Gary Oldman of cell types” to reverse aging
UCLA scientists on track to develop a stem cell replacement therapy for Duchenne Muscular Dystrophy
Last year, we wrote about a CIRM-funded team at UCLA that’s on a mission to develop a stem cell treatment for patients with Duchenne muscular dystrophy (DMD). Today, we bring you an exciting update on this research just in time for the holidays (Merry Christmas and Happy Hanukkah and Kwanza to our readers!). DMD is … Continue reading UCLA scientists on track to develop a stem cell replacement therapy for Duchenne Muscular Dystrophy
Turning the corner with the FDA and NIH; CIRM creates new collaborations to advance stem cell research
This blog is part of the Month of CIRM series on the Stem Cellar A lot can change in a couple of years. Just take our relationship with the US Food and Drug Administration (FDA). When we were putting together our Strategic Plan in 2015 we did a survey of key players and stakeholders at … Continue reading Turning the corner with the FDA and NIH; CIRM creates new collaborations to advance stem cell research
The Stem Cellar 