3D illustration of an antibody binding to a designated target. Illustration created by Audra Geras. A variety of diseases can be traced to a simple root cause: problems in the bone marrow. The bone marrow contains specialized stem cells known as hematopoietic stem cells (HSCs) that give rise to different types of blood cells. As … Continue reading Antibody effective in cure for rare blood disorders
chemotherapy
New hope for stem cell therapy in patients with leukemia
Of the many different kinds of cancer that affect humans, leukemia is the most common in young people. As with many types cancer, doctors mostly turn to chemotherapy to treat patients. Chemotherapy, however, comes with its own share of issues, primarily severe side effects and the constant threat of disease recurrence. Stem cell therapy treatment … Continue reading New hope for stem cell therapy in patients with leukemia
Surprise findings about bone marrow transplants could lead to more effective stem cell therapies
Some medical therapies have been around for so long that we naturally assume we understand how they work. That’s not always the case. Take aspirin for example. It’s been used for more than 4,000 years to treat pain and inflammation but it was only in the 1970’s that we really learned how it works. The … Continue reading Surprise findings about bone marrow transplants could lead to more effective stem cell therapies
Stem cell stories that caught our eye: a surprising benefit of fasting, faster way to make iPSCs, unlocking the secret of leukemia cancer cells
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Is fasting the fountain of youth? Among the many insults our bodies endure in old age is a weakened immune system which leaves the elderly … Continue reading Stem cell stories that caught our eye: a surprising benefit of fasting, faster way to make iPSCs, unlocking the secret of leukemia cancer cells
Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk
The good news is you’re cancer free, the bad news is you need a heart transplant. It almost sounds like the punchline to a joke, but it’s no laugher matter because the scenario is real for some cancer patients. Chemotherapy is a life saver for many but certain doses can be so toxic that it’s often hard … Continue reading Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk
Combination Cancer Therapy Gives Cells a Knockout Punch
For some forms of cancer, there really is no way to truly eradicate it. Even the most advanced chemotherapy treatments leave behind some straggler cells that can fuel a relapse. But now, scientists have devised a unique strategy, something they are calling a ‘one-two punch’ that can more effectively wipe out dangerous tumors, and lower … Continue reading Combination Cancer Therapy Gives Cells a Knockout Punch
Clever Stem Cells Withstand Chemo Drug’s Harmful Side Effects
For some conditions, it seem that the treatment can cause almost as many problems as than the disease itself. That’s often the case with some forms of cancer, such as acute lymphoblastic leukemia. The most common type of cancer to affect children, treatment usually involves chemotherapy with the drug methotrexate (MTX). And, while effective at … Continue reading Clever Stem Cells Withstand Chemo Drug’s Harmful Side Effects
Out with the Old and in with the New: Starvation Sparks Stem Cells to Replenish Immune System
New research from California scientists has revealed a startling side effect to prolonged starvation, or fasting. In the latest issue of the journal Cell Stem Cell, scientists from the University of Southern California describe how fasting triggers the human immune system to flush out old, damaged cells and replace them with new ones. This marks … Continue reading Out with the Old and in with the New: Starvation Sparks Stem Cells to Replenish Immune System
The Stem Cellar 