Old therapies inspire new hope for treatment of pediatric brain tumors

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Image courtesy St. Jude Children's Research Hospital A recent study led by John Hopkins Medicine has found that combining two 'old therapies' can offer a surprising new purpose - fighting Medulloblastoma, the most common malignant brain tumor in children. The fast-growing cancerous tumor originates in the brain … Continue reading Old therapies inspire new hope for treatment of pediatric brain tumors

Two studies identify a molecule that could be used to block Zika virus and kill cancer cells

Dr. Tariq Rana (left) and Dr. Jeremy Rich (right) both lead independent teams at UC San Diego that identified a molecule, αvβ5 integrin, as the Zika virus' key to getting into brain stem cells Zika virus is caused by a virus transmitted by Aedes mosquitoes. People usually develop mild symptoms that include fever, rash, and … Continue reading Two studies identify a molecule that could be used to block Zika virus and kill cancer cells

Drug used to treat multiple sclerosis may improve glioblastoma outcomes

Dr. Jeremy Rich, UC San Diego Glioblastoma is an aggressive form of cancer that invades brain tissue, making it extremely difficult to treat. Current therapies involving radiation and chemotherapy are effective in destroying the bulk of brain cancer cells, but they are not able to reach the brain cancer stem cells, which have the ability … Continue reading Drug used to treat multiple sclerosis may improve glioblastoma outcomes

Facebook Live – Ask the Stem Cell Team about Patient Advocacy

How often do you get to ask an expert a question about something that matters deeply to you and get an answer right away? Not very often I'm guessing. That's why CIRM's Facebook Live "Ask the Stem Cell Team About Patient Advocacy" gives you a chance to do just that this Thursday, March 14th from … Continue reading Facebook Live – Ask the Stem Cell Team about Patient Advocacy

Targeted treatment for pediatric brain tumors shows promising results

Image of medulloblastoma Imagine sitting in the doctor's office and being told the heartbreaking news that your child has been diagnosed with a malignant brain tumor. As one might expect, the doctor states that the most effective treatment option is typically a combination of chemotherapy and radiation. However, the doctor reveals that there are additional … Continue reading Targeted treatment for pediatric brain tumors shows promising results

Novel approach to slowing deadly brain cancer stem cells may lead to new treatments

Glioblastoma, a form of brain cancer, is one of the most dreaded cancer diagnoses. Standard radiation and chemotherapy treatments for glioblastoma almost always prove ineffective because of the cancer’s ability to grow back. With their unlimited potential to self-renew, cancer stem cells within the brain tumor are thought to be responsible for its aggressive reoccurrence. … Continue reading Novel approach to slowing deadly brain cancer stem cells may lead to new treatments

Taking a new approach to fighting a deadly brain cancer

CIRM’s 2017 Annual Report will be going live online very soon. In anticipation of that we are highlighting some of the key elements from the report here on the Stem Cellar. One of the most exciting new approaches in targeting deadly cancers is chimeric antigen receptor (CAR) T-cell therapy, using the patient’s own immune system … Continue reading Taking a new approach to fighting a deadly brain cancer

CIRM-Funded Clinical Trials Targeting Cancers

Welcome to the Month of CIRM! As we mentioned in last Thursday’s blog, during the month of October we’ll be looking back at what CIRM has done since the agency was created by the people of California back in 2004. To start things off, we’ll be focusing on CIRM-funded clinical trials this week. Supporting clinical … Continue reading CIRM-Funded Clinical Trials Targeting Cancers

Genetically engineered immune cells melt away deadly brain tumors

Cancers come in many different forms. Some are treatable if caught early and other aren’t. One of the most deadly types of cancers are glioblastomas - a particularly aggressive form of brain tumor.  Patients diagnosed with glioblastoma have an average life expectancy of 12-15 months and there is no cure or effective treatment that extends … Continue reading Genetically engineered immune cells melt away deadly brain tumors

Scientists use human stem cell models to target deadly brain cancer

Malignant brain cancer is a devastating disease and it’s estimated that more than 16,000 patients will die of it this year. One of the most aggressive forms of brain cancer is gliomas, which originate from the support cells in the brain or spine that keep nerve cells happy and functioning. Unfortunately, there is no cure … Continue reading Scientists use human stem cell models to target deadly brain cancer