Scientists Make Insulin-Secreting Cells from Stem Cells of Type 1 Diabetes Patients

Stem cell research for diabetes is in a Golden Age. In the past few years, scientists have developed methods to generate insulin-secreting pancreatic beta cell-like cells from embryonic stem cells, induced pluripotent stem cells (iPS cells), and even directly from human skin. We’ve covered a number of recent studies in this area on our blog, … Continue reading Scientists Make Insulin-Secreting Cells from Stem Cells of Type 1 Diabetes Patients

UCSD scientists find new clue into how Zika virus impairs brain development

In April of this year, the Centers for Disease Control and Prevention (CDC) announced their conclusion that Zika virus causes microcephaly, a birth defect that results in abnormal brain development and a smaller sized head in infants. Rather than a single study being responsible for their conclusion, the CDC argued that “mounting evidence” from multiple … Continue reading UCSD scientists find new clue into how Zika virus impairs brain development

On the Hunt for Huntington’s Disease Treatments in the New Millennium

“Over the next five to ten years, we want to make Huntington’s disease an increasingly treatable condition.” This bold and inspiring statement was made by Dr. Ray Dorsey at the inaugural HD-CARE symposium for Huntington’s disease (HD) research held at UC Irvine last month. The event brought together scientists, doctors, patients, family members, and caregivers … Continue reading On the Hunt for Huntington’s Disease Treatments in the New Millennium

Learning about the Potential of Stem Cells? There’s an App for that.

Staying informed about stem cell research is an important but daunting task. With all of the scientific lingo, the hundreds of websites, and the multitude of diseases related to stem cell research, it's a perfect storm of information overload. For our readers who feel swept up in those waves at times (or most of the … Continue reading Learning about the Potential of Stem Cells? There’s an App for that.

An inside look reveals the adult brain prunes its own branches

Did you know that when you’re born, your brain contains around 100 billion nerve cells? This is impressive considering that these nerve cells, also called neurons, are already connected to each other through an intricate, complex neural network that is essential for brain function. Here’s how the brain does it. During development, neural stem cells … Continue reading An inside look reveals the adult brain prunes its own branches

Double dose of good news: scientists use drugs to turn skin into heart and brain cells

Today the stem cell field got a double dose of good news. Two CIRM-funded studies from the Gladstone Institutes reported successfully reprogramming human skin into heart cells and brain cells in a dish using different cocktails of small molecule drugs. The work was led by Dr. Sheng Ding, a Senior Investigator at the Gladstone Institutes. … Continue reading Double dose of good news: scientists use drugs to turn skin into heart and brain cells

UCSF study explains how chronic inflammation impairs blood stem cell function

Inflammation is the immune system’s natural protective response to infection and injury. It involves the activation and mobilization of immune cells that can kill off foreign invaders and help repair damaged tissue. At the heart of the inflammatory response are hematopoietic stem cells (HSCs). These are blood stem cells found in the bone marrow that … Continue reading UCSF study explains how chronic inflammation impairs blood stem cell function

A visual guide on using stem cells to treat blindness

Some stories are so sweet or powerful or wonderful - or all three - that they just stick in your mind. About 18 months ago Rosalinda and German Barrero came to talk to the CIRM Board about retinitis pigmentosa (RP), a devastating genetic disease that slowly destroys a person’s vision. Contrary to what everyone expected … Continue reading A visual guide on using stem cells to treat blindness

Stem cell stories that caught our eye: fashionable stem cells, eliminating HIV, cellular Trojan horse fights cancer

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Stem cell fashion for a cause. Science and art are not mutually exclusive subjects. I know plenty of scientists who are talented painters or designers. … Continue reading Stem cell stories that caught our eye: fashionable stem cells, eliminating HIV, cellular Trojan horse fights cancer

Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development

The great inventions – like the automobile, the Internet or aviation – are marked as important turning points in human history. But it’s usually the additional tinkering that goes on in the ensuing years after the initial invention that makes the technology feasible in terms of cost, reproducibility and mass production. The same holds true … Continue reading Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development