Stem cell stories that caught our eye: two-week old embryos in the lab, gene edited disease model, recipe for bone and cancer milestone

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Two-week embryos grabbed headlines. I have rarely seen as many online news outlets pick up a basic science story as happened this week with the … Continue reading Stem cell stories that caught our eye: two-week old embryos in the lab, gene edited disease model, recipe for bone and cancer milestone

On the Hunt for Huntington’s Disease Treatments in the New Millennium

“Over the next five to ten years, we want to make Huntington’s disease an increasingly treatable condition.” This bold and inspiring statement was made by Dr. Ray Dorsey at the inaugural HD-CARE symposium for Huntington’s disease (HD) research held at UC Irvine last month. The event brought together scientists, doctors, patients, family members, and caregivers … Continue reading On the Hunt for Huntington’s Disease Treatments in the New Millennium

An inside look reveals the adult brain prunes its own branches

Did you know that when you’re born, your brain contains around 100 billion nerve cells? This is impressive considering that these nerve cells, also called neurons, are already connected to each other through an intricate, complex neural network that is essential for brain function. Here’s how the brain does it. During development, neural stem cells … Continue reading An inside look reveals the adult brain prunes its own branches

Stem cell stories that caught our eye: Trifecta of nerve news on aging, Parkinson’s and myelin diseases, also expanding cord blood

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. To save nerves, make them slow down. Nerves, like all cells, constantly make protein, but that task uses up a lot of energy and older … Continue reading Stem cell stories that caught our eye: Trifecta of nerve news on aging, Parkinson’s and myelin diseases, also expanding cord blood

Double dose of good news: scientists use drugs to turn skin into heart and brain cells

Today the stem cell field got a double dose of good news. Two CIRM-funded studies from the Gladstone Institutes reported successfully reprogramming human skin into heart cells and brain cells in a dish using different cocktails of small molecule drugs. The work was led by Dr. Sheng Ding, a Senior Investigator at the Gladstone Institutes. … Continue reading Double dose of good news: scientists use drugs to turn skin into heart and brain cells

Achilles’ Heel of Brain Cancer Identified in Tumor Stem Cells

Few words strike me with more dread than glioblastoma, the name for a very aggressive, incurable cancer of the brain. Although surgery and chemotherapy can help hold off or reverse a glioblastoma’s growth for a while, almost inevitably the tumor comes back along with a terrible prognosis: an average survival time of 12 to 15 … Continue reading Achilles’ Heel of Brain Cancer Identified in Tumor Stem Cells

UCSF study explains how chronic inflammation impairs blood stem cell function

Inflammation is the immune system’s natural protective response to infection and injury. It involves the activation and mobilization of immune cells that can kill off foreign invaders and help repair damaged tissue. At the heart of the inflammatory response are hematopoietic stem cells (HSCs). These are blood stem cells found in the bone marrow that … Continue reading UCSF study explains how chronic inflammation impairs blood stem cell function

A visual guide on using stem cells to treat blindness

Some stories are so sweet or powerful or wonderful - or all three - that they just stick in your mind. About 18 months ago Rosalinda and German Barrero came to talk to the CIRM Board about retinitis pigmentosa (RP), a devastating genetic disease that slowly destroys a person’s vision. Contrary to what everyone expected … Continue reading A visual guide on using stem cells to treat blindness

Stem cell stories that caught our eye: fashionable stem cells, eliminating HIV, cellular Trojan horse fights cancer

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Stem cell fashion for a cause. Science and art are not mutually exclusive subjects. I know plenty of scientists who are talented painters or designers. … Continue reading Stem cell stories that caught our eye: fashionable stem cells, eliminating HIV, cellular Trojan horse fights cancer

Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development

The great inventions – like the automobile, the Internet or aviation – are marked as important turning points in human history. But it’s usually the additional tinkering that goes on in the ensuing years after the initial invention that makes the technology feasible in terms of cost, reproducibility and mass production. The same holds true … Continue reading Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development