UCLA launches CIRM-funded clinical trial using engineered blood stem cells to fight hard-to-treat cancers

It’s not uncommon for biomedical institutes as well as their funding partners to announce through press releases that a clinical trial they’re running has gotten off the ground and has started to enroll patients. For an outsider looking in, it may seem like they’re jumping the gun a bit. No patients have received the therapy. … Continue reading UCLA launches CIRM-funded clinical trial using engineered blood stem cells to fight hard-to-treat cancers

Stem Cell Stories That Caught our Eye: Duchenne muscular dystrophy and short telomeres, motor neurons from skin, and students today, stem cell scientists tomorrow

Short telomeres associated with Duchenne Muscular Dystrophy. Duchenne Muscular Dystrophy (DMD) is a severe muscle wasting disease that typically affects young men. There is no cure for DMD and the average life expectancy is 26. These are troubling facts that scientists at the University of Pennsylvania are hoping to change with their recent findings in … Continue reading Stem Cell Stories That Caught our Eye: Duchenne muscular dystrophy and short telomeres, motor neurons from skin, and students today, stem cell scientists tomorrow

Hearts and brains are center stage at CIRM Patient Advocate event

Describing the work of a government agency is not the most exciting of topics. Books on the subject would probably be found in the “Self-help for Insomniacs” section of a good bookstore (there are still some around). But at CIRM we are fortunate. When we talk about what we do, we don’t talk about the … Continue reading Hearts and brains are center stage at CIRM Patient Advocate event

Taming the Zika virus to kill cancer stem cells that drive lethal brain tumor

An out of control flame can be very dangerous, even life-threatening. But when harnessed, that same flame sustains life in the form of warm air, a source of light, and a means to cook. A similar duality holds true for viruses. Once it infects the body, a virus can replicate like wildfire and cause serious … Continue reading Taming the Zika virus to kill cancer stem cells that drive lethal brain tumor

Stories that caught our eye last week: dying cells trigger stem cells, CRISPR videogames and an obesity-stem cell link

A dying cell’s last breath triggers stem cell division. Most cells in your body are in a constant state of turnover. The cells of your lungs, for instance, replace themselves every 2 to 3 weeks and, believe it or not, you get a new intestine every 2 to 3 days. We can thank adult stem cells … Continue reading Stories that caught our eye last week: dying cells trigger stem cells, CRISPR videogames and an obesity-stem cell link

Stem cell therapy for Parkinson’s disease shows promise in monkeys

Tremors, muscle stiffness, shuffling, slow movement, loss of balance. These are all symptoms of Parkinson’s disease (PD), a neurodegenerative disorder that progressively destroys the dopamine-producing neurons in the brain that control movement. While there is no cure for Parkinson’s disease, there are drugs like Levodopa and procedures like deep brain stimulation that alleviate or improve … Continue reading Stem cell therapy for Parkinson’s disease shows promise in monkeys

Extra dose of patience needed for spinal cord injury stem cell therapies, rat study suggests

2017 has been an exciting year for Asterias Biotherapeutics’ clinical trial which is testing a stem cell-based therapy for spinal cord injury. We’ve written several stories about patients who have made remarkable recoveries after participating in the trial (here and here). But that doesn’t mean researchers at other companies or institutes who are also investigating spinal … Continue reading Extra dose of patience needed for spinal cord injury stem cell therapies, rat study suggests

Stem cell stories that caught our eye: bubble baby therapy a go in UK, in-utero stem cell trial and novel heart disease target

There were lots of CIRM mentions in the news this week. Here are two brief recaps written by Karen Ring to get you up to speed. A third story by Todd Dubnicoff summarizes an promising finding related to heart disease by researchers in Singapore.   CIRM-funded “bubble baby” disease therapy gets special designation by UK. … Continue reading Stem cell stories that caught our eye: bubble baby therapy a go in UK, in-utero stem cell trial and novel heart disease target

Confusing cancer to kill it

Confusion is not a state of mind that we usually seek out. Being bewildered is bad enough when it happens naturally, so why would anyone actively pursue it? But now some researchers are doing just that, using confusion to not just block a deadly blood cancer, but to kill it. Today the CIRM Board approved … Continue reading Confusing cancer to kill it

New research suggests taking a daily dose of vitamin C could prevent leukemia

Did you take your vitamins today? It’s not always easy to remember with such busy lives, but after you read this blog, you’ll be sure to make vitamins part of your daily routine if you haven’t already! Two recent studies, published in the journals Nature and Cell, reported that vitamin C has a direct impact … Continue reading New research suggests taking a daily dose of vitamin C could prevent leukemia