On a Sunday morning in early 2016, Lucas Lindner was driving to get some donuts for his grandmother. A deer jumped in front of his truck. Lucas swerved to avoid it and crashed, suffering a severe spinal cord injury that left him paralyzed from the neck down. Lucas took part in a CIRM-funded clinical trial, … Continue reading How a stem cell transplant may help transform Lucas Lindner’s life
Asterias Biotherapeutics
Positive update on Asterias’ SCiStar study for spinal cord injury at TMM 2017
This guest blog is reposted with permission from Signals Blog, published by the Center for Commercialization of Regenerative Medicine (CCRM) in Canada. With the extensive exploitation of regenerative medicine through the marketing and selling of unapproved stem cell “therapies” online, it was refreshing to hear an update about clinical trials for a legitimate stem cell … Continue reading Positive update on Asterias’ SCiStar study for spinal cord injury at TMM 2017
Turning the corner with the FDA and NIH; CIRM creates new collaborations to advance stem cell research
This blog is part of the Month of CIRM series on the Stem Cellar A lot can change in a couple of years. Just take our relationship with the US Food and Drug Administration (FDA). When we were putting together our Strategic Plan in 2015 we did a survey of key players and stakeholders at … Continue reading Turning the corner with the FDA and NIH; CIRM creates new collaborations to advance stem cell research
CIRM-Funded Clinical Trials Targeting Brain and Eye Disorders
This blog is part of our Month of CIRM series, which features our Agency’s progress towards achieving our mission to accelerate stem cell treatments to patients with unmet medical needs. This week, we’re highlighting CIRM-funded clinical trials to address the growing interest in our rapidly expanding clinical portfolio. Our Agency has funded a total of … Continue reading CIRM-Funded Clinical Trials Targeting Brain and Eye Disorders
Extra dose of patience needed for spinal cord injury stem cell therapies, rat study suggests
2017 has been an exciting year for Asterias Biotherapeutics’ clinical trial which is testing a stem cell-based therapy for spinal cord injury. We’ve written several stories about patients who have made remarkable recoveries after participating in the trial (here and here). But that doesn’t mean researchers at other companies or institutes who are also investigating spinal … Continue reading Extra dose of patience needed for spinal cord injury stem cell therapies, rat study suggests
CIRM weekly stem cell roundup: minibrain model of childhood disease; new immune insights; patient throws out 1st pitch
New human Mini-brain model of devastating childhood disease. The eradication of Aicardi-Goutieres Syndrome (AGS) can’t come soon enough. This rare but terrible inherited disease causes the immune system to attack the brain. The condition leads to microcephaly (an abnormal small head and brain size), muscle spasms, vision problems and joint stiffness during infancy. Death or … Continue reading CIRM weekly stem cell roundup: minibrain model of childhood disease; new immune insights; patient throws out 1st pitch
Stem cell stories that caught our eye: skin grafts fight diabetes, reprogramming the immune system, and Asterias expands spinal cord injury trial sites
Here are the stem cell stories that caught our eye this week. Skin grafts fight diabetes and obesity. An interesting new gene therapy strategy for fighting type 1 diabetes and obesity surfaced this week. Scientists from the University of Chicago made genetically engineered skin grafts that secrete a peptide hormone called glucagon-liked peptide-1 (GLP-1). This … Continue reading Stem cell stories that caught our eye: skin grafts fight diabetes, reprogramming the immune system, and Asterias expands spinal cord injury trial sites
Stories that caught our eye: Spinal cord injury trial milestone, iPS for early cancer diagnosis, and storing videos in DNA
Spinal cord injury clinical trial hits another milestone (Kevin McCormack) We began the week with good news about our CIRM-funded clinical trial with Asterias for spinal cord injury, and so it’s nice to end the week with more good news from that same trial. On Wednesday, Asterias announced it had completed enrolling and dosing patients … Continue reading Stories that caught our eye: Spinal cord injury trial milestone, iPS for early cancer diagnosis, and storing videos in DNA
CIRM-funded stem cell clinical trial for spinal cord injury expands patient recruitment
It’s always great to start the week off with some good news. Today we learned that the Food and Drug Administration (FDA) has given Asterias Biotherapeutics approval to expand the number and type of people with spinal cord injuries that it treats in their CIRM-funded clinical trial. Up till now, Asterias has been treating people … Continue reading CIRM-funded stem cell clinical trial for spinal cord injury expands patient recruitment
Stories that caught our eye: An antibody that could make stem cell research safer; scientists prepare for clinical trial for Parkinson’s disease; and the stem cell scientist running for Congress
Antibody to make stem cells safer: There is an old Chinese proverb that states: ‘What seems like a blessing could be a curse’. In some ways that proverb could apply to stem cells. For example, pluripotent stem cells have the extraordinary ability to turn into many other kinds of cells, giving researchers a tool to … Continue reading Stories that caught our eye: An antibody that could make stem cell research safer; scientists prepare for clinical trial for Parkinson’s disease; and the stem cell scientist running for Congress