Although heart muscle cells, or cardiomyocytes, are specialized to help pump blood to the organs, they nonetheless carry all the genetic instructions for becoming a nerve cell, an intestinal cell, a liver or any cell type in the body. But at the moment in time that the fetal heart begins to develop, master switch proteins, … Continue reading Understanding two heart problems by studying the domino effect of one gene network
Author: Todd Dubnicoff
Stem cell stories that caught our eye: insights into stem cell biology through telomeres, reprogramming and lung disease
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Telomeres and stem cell stability: too much of a good thing Just like those plastic tips at the end of shoelaces (fun fact: they’re called … Continue reading Stem cell stories that caught our eye: insights into stem cell biology through telomeres, reprogramming and lung disease
New iPS Insights: Cell Damage Enhances Reprogramming
Researchers learn a ton about the biological function of cells by studying them in vitro; that is, outside the body in a petri dish. But inside the body, or in vivo, cells respond to surrounding proteins and other cells that may be missing in an in vitro experiment. Important insights waiting to be revealed can … Continue reading New iPS Insights: Cell Damage Enhances Reprogramming
Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Horsing around at the World Stem Cell Summit The World Stem Cell Summit (WSCS) is coming up very shortly (December 6-9) in lovely downtown West Palm Beach, Florida. And this year it has an added attraction; horses. For my money the WSCS is the most enjoyable of the many conferences held around the US focusing … Continue reading Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Measuring depression with non-invasive imaging of new brain cells
For most of the 20th century, scientists thought you’re basically stuck with the brain cells you’re born with. “Everything may die, nothing may be regenerated”, is how Santiago Ramón y Cajal, the father of modern neuroscience, described nerve cells, aka neurons, in the adult brain. But, over the past few decades, it’s become clear that … Continue reading Measuring depression with non-invasive imaging of new brain cells
With CRISPR-Cas9, Stanford Team Looks for Landslide Victory over Sickle Cell Disease
The results are in folks. Though it’s too early to declare a winner, it looks very likely that sickle cell disease is going to be soundly defeated by CRISPR-Cas9. Reporting in Nature on Monday, Stanford researchers devised a method to efficiently correct the sickle cell mutation in human blood stem cells using the super-popular, user-friendly … Continue reading With CRISPR-Cas9, Stanford Team Looks for Landslide Victory over Sickle Cell Disease
Stem cell stories that caught our eye: Amy Schumer’s MS fundraising; healing traumatic brain injury; schizophrenia iPS insights
Amy Schumer and Paul Shaffer raise money for MS. (Karen Ring) Two famous individuals, one a comedian/movie star, the other a well-known musician, have combined forces to raise money for an important cause. Amy Schumer and Paul Shaffer have pledged to raise $2.5 million dollars to help support research into multiple sclerosis (MS). This disease … Continue reading Stem cell stories that caught our eye: Amy Schumer’s MS fundraising; healing traumatic brain injury; schizophrenia iPS insights
Investing in student researchers now for future stem cell therapy homeruns
Even though my San Francisco Giants didn’t make it to the World Series this year, I still watched Game 1 two nights ago between the Cleveland Indians and the Chicago Cubs. As each batter stepped up to the plate for their first at bat, I thought about all the years of training and in-game experience … Continue reading Investing in student researchers now for future stem cell therapy homeruns
Stem cell stories that caught our eye: Blood stem cells on a diet, Bladder control after spinal cord injuries, new ALS insights
Putting blood stem cells on a diet. (Karen Ring) Scientists from Stanford and the University of Tokyo have figured out a new way to potentially make bone marrow transplants more safe. Published yesterday in the journal Science, the teams discovered that removing an essential amino acid, called valine, from the diets of mice depleted their … Continue reading Stem cell stories that caught our eye: Blood stem cells on a diet, Bladder control after spinal cord injuries, new ALS insights
Know Your Stem Cell History with Gladstone’s Interactive Timeline Tool
Stem cell biology is such a young area of research. It was only in 1998 that the first human embryonic stem cell line was generated by Jamie Thomson. A dizzying amount of breakthrough research has occurred in that short span of time, including the Nobel Prize winning work of Shinya Yamanaka for devising a method … Continue reading Know Your Stem Cell History with Gladstone’s Interactive Timeline Tool
The Stem Cellar 