How a rare and fatal childhood disorder brought two families together and helped reinforce a life-changing decision

When you are told your newborn child has a life-threatening condition and needs immediate help, your world tends to get very small very fast. All you are focused on is making the right decision to save your child. That’s what happened with Pawash and Upasana, the parents of Ronav (“Ronnie”) Kashyap. When they were told … Continue reading How a rare and fatal childhood disorder brought two families together and helped reinforce a life-changing decision

High profile journal takes on clinics offering unproven therapies

The Journal of the American Medical Association, better known as JAMA, is a prestigious peer-reviewed journal that is not for the faint of heart. Its articles are dense scientific studies with equally dense titles – such as ‘Transendocardial Mesenchymal Stem Cells and Mononuclear Bone Marrow Cells for Ischemic Cardiomyopathy’. But a recent article was a … Continue reading High profile journal takes on clinics offering unproven therapies

A 3-D model of heart tissue gives scientists a leg up in studying heart disease

Hank Gathers was a 23-year-old basketball player at Loyola Marymount University with numerous accolades to his name and a promising future in the sport. This all came to an end when he suddenly collapsed in the middle of one of his games and subsequently passed away.  It was the beginning of numerous such sudden death … Continue reading A 3-D model of heart tissue gives scientists a leg up in studying heart disease

Stem Cell Stories that Caught Our Eye: Human Eggs From Stem Cells, A New Way to Heal Broken Bones and A Lab Grown Esophagus

Stem cell image of the week:  Immature human eggs (pink) were created by Japanese researchers using stem cells that were derived from blood cells. A team of Japanese scientists say they have taken an important step toward creating human eggs in a lab dish. Their work, which was reported Thursday in the journal Science, outlined their research and explained … Continue reading Stem Cell Stories that Caught Our Eye: Human Eggs From Stem Cells, A New Way to Heal Broken Bones and A Lab Grown Esophagus

New partnership to make CIRM supported treatment for type 1 diabetes even better

  ViaCyte, a regenerative medicine company long backed by CIRM, announced a partnership with CRISPR Therapeutics to increase the number of people with Type 1 Diabetes (T1D) who could benefit from their PEC-Direct therapeutic implant. Last year, CIRM granted ViaCyte $20 million to facilitate development of PEC-Direct, a device that both transplants pancreatic progenitor stem … Continue reading New partnership to make CIRM supported treatment for type 1 diabetes even better

New Method to Create Human Neural Stem Cells May Regenerate Spine in Rats

  Scientists at the University of California San Diego School of Medicine have created spinal cord neural stem cells (NSC) from human pluripotent stem cells (hPSCs), which could feasibly represent a source of transplantable cells for repairing spinal cord injuries. The research, which was published in the journal Nature Methods, showed that the human spinal … Continue reading New Method to Create Human Neural Stem Cells May Regenerate Spine in Rats

California’s Stem Cell Agency Accelerates Treatments to Patients

The following article is an Op Ed that appeared in today's print version of the San Francisco Chronicle Biotechnology was born in California in the 1970s based on the discovery out of one of its universities and California is responsible for an industry that has impacted the lives of billions of people worldwide. In 2004, … Continue reading California’s Stem Cell Agency Accelerates Treatments to Patients

A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer

A Phase 1 clinical trial co-sponsored by CIRM and Oncternal Therapeutics, has started treating patients at UC San Diego (UCSD). The goal of the trial is to test the safety and anti-tumor activity of the Oncternal-developed drug, cirmtuzumab, in treating breast cancer. Breast cancer is the second most common cancer to occur in women, regardless … Continue reading A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer

Stem Cell Stories that Caught Our Eye: Killer Cells May Treat Cancer, CIRM-Funded Trial Shows Promise and Worms to the Rescue – New Research Could Lead to Human Therapies

Stem cell image of the week:  Our stem cell image of the week shows natural killer cells (yellow) attacking a cancer cell (red). The cancer fighters known as CAR T cells have proved their prowess in recent years. Three therapies using the altered T cells against lymphoma or leukemia have won U.S. Food and Drug … Continue reading Stem Cell Stories that Caught Our Eye: Killer Cells May Treat Cancer, CIRM-Funded Trial Shows Promise and Worms to the Rescue – New Research Could Lead to Human Therapies

Deep dive into muscle repair yields new strategies to combat Duchenne muscular dystrophy

Researchers at the Sanford Burnham Prebys Medical Discovery Institute (SBP) reported new findings this week that may lead to novel therapeutic strategies for people suffering from Duchenne muscular dystrophy (DMD). DMD, a muscle-wasting disease that affects 1 in 7250 males aged 5 to 24 years in the United States, is caused by a genetic mutation leading … Continue reading Deep dive into muscle repair yields new strategies to combat Duchenne muscular dystrophy