While we have made great progress in developing therapies that control the AIDS virus, HIV/AIDS remains a chronic condition and HIV medicines themselves can give rise to a new set of medical issues. That’s why the Board of the California Institute for Regenerative Medicine (CIRM) has awarded $3.8 million to a team from City of Hope … Continue reading Stem Cell Agency Invests in New Immunotherapy Approach to HIV, Plus Promising Projects Targeting Blindness and Leukemia
The Scripps Research Institute
Using biological “codes” to generate neurons in a dish
Investigators at the Scripps Research Institute are making brain waves in the field of neuroscience. Until now, neuroscience research has largely relied on a variety of animal models to understand the complexities of various brain or neuronal diseases. While beneficial for many reasons, animal models do not always allow scientists to understand the precise mechanism … Continue reading Using biological “codes” to generate neurons in a dish
Celebrating Exciting CIRM-Funded Discovery Research on World Parkinson’s Day
April 11th is World Parkinson’s Disease Awareness Day. To mark the occasion, we’re featuring the work of CIRM-funded researchers who are pursuing new, promising ideas to treat patients with this debilitating neurodegenerative disease. Birgitt Schuele, Parkinson’s Institute CIRM Grant: Quest Award – Discovery Stage Research Research: Birgitt and her team at the Parkinson’s Institute in … Continue reading Celebrating Exciting CIRM-Funded Discovery Research on World Parkinson’s Day
Scientists find switch that targets immunotherapies to solid tumors
Cancer immunotherapies harness the power of the patient’s own immune system to fight cancer. One type of immunotherapy, called adoptive T cell therapy, uses immune cells called CD8+ Killer T cells to target and destroy tumors. These T cells are made in the spleen and lymph nodes and they can migrate to different locations in … Continue reading Scientists find switch that targets immunotherapies to solid tumors
CIRM-funded scientists discover a new way to make stem cells using antibodies
Just as learning a new skill takes time to hone, scientific discoveries take time to perfect. Such is the case with induced pluripotent stem cells (iPSCs), the Nobel Prize winning technology that reprograms mature adult cells back into a pluripotent stem cell state. iPSCs are a powerful tool because they can develop into any cell … Continue reading CIRM-funded scientists discover a new way to make stem cells using antibodies
Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell transplants help put MS in remission: A combination of high dose immunosuppressive therapy and transplant of a person’s own blood stem cells seems to be a powerful tool in helping people with relapsing-remitting multiple sclerosis (RRMS) go into sustained remission. Multiple sclerosis (MS) is an autoimmune disorder where the body’s own immune system … Continue reading Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
A TWIST in mesenchymal stem cell trials: protein predicts therapy’s potential
Mesenchymal stem cells are adult stem cells with the potential to specialize into a somewhat limited number of cell types – those responsible for making fat, bone and cartilage. But MSCs are also known for their anti-inflammatory properties which are carried out via the release of protein factors. This ability to dampen the immune system … Continue reading A TWIST in mesenchymal stem cell trials: protein predicts therapy’s potential
Cell survival strategy gives mesenchymal stem cells their “paramedic” properties
A cell for all therapies Type “mesenchymal stem cells” into the federal online database of registered clinical trials, and you’ll get a sprawling list of 527 trials testing treatments for diabetes, multiple sclerosis as well as diseases of the kidney, lung, and heart, to name just a few. Mesenchymal stem cells (MSCs) have the capacity … Continue reading Cell survival strategy gives mesenchymal stem cells their “paramedic” properties
Goodnight, Stem Cells: How Well Rested Cells Keep Us Healthy
Plenty of studies show that a lack of sleep is nothing but bad news and can contribute to a whole host of health problems like heart disease, poor memory, high blood pressure and obesity. In a sense, the same holds true for the stem cells in our body. In response to injury, adult stem cells … Continue reading Goodnight, Stem Cells: How Well Rested Cells Keep Us Healthy
CIRM-Funded Scripps Team Replicates Pain in a Lab Dish; Seeks New Treatments for Chronic Sufferers
Pain hurts but it also protects. Thanks to nerve cells called sensory neurons, which weave their nerve fibers throughout our skin and other tissues, we are alerted to dangerous events like touching a hot plate or even to the sense of having a full bladder. However, trauma such as a spinal cord injury or diseases … Continue reading CIRM-Funded Scripps Team Replicates Pain in a Lab Dish; Seeks New Treatments for Chronic Sufferers
The Stem Cellar 