Brave new world or dark threatening future: a clear-eyed look at genome editing and what it means for humanity

   Is this the face of the future? “Have you ever wished that there were something different about yourself? Maybe you imagined yourself taller, thinner or stronger? Smarter? More attractive? Healthier?” That’s the question posed by UC Davis stem cell researcher (and CIRM grantee) Paul Knoepfler at the start of his intriguing new book ‘GMO … Continue reading Brave new world or dark threatening future: a clear-eyed look at genome editing and what it means for humanity

Achilles’ Heel of Brain Cancer Identified in Tumor Stem Cells

Few words strike me with more dread than glioblastoma, the name for a very aggressive, incurable cancer of the brain. Although surgery and chemotherapy can help hold off or reverse a glioblastoma’s growth for a while, almost inevitably the tumor comes back along with a terrible prognosis: an average survival time of 12 to 15 … Continue reading Achilles’ Heel of Brain Cancer Identified in Tumor Stem Cells

New study says stem cells derived from older people may have more problems than we thought.

Ever since 2006 when Japanese researcher Shinya Yamanaka showed that you could take an adult cell, such as those in your skin, and reprogram it to act like an embryonic stem cell, the scientific world has looked at these induced pluripotent stem (iPS) cells as a potential game changer. They had the ability to convert … Continue reading New study says stem cells derived from older people may have more problems than we thought.

Patient Advocates find their voice in a different language

Packed house for stem cell conference in Tokyo - Adrienne Shapiro front row, second from right One of the many wonderful things about travel is that it opens up your eyes and mind to the fact that, while there are many ways in which people around the world differ from each other, there are also … Continue reading Patient Advocates find their voice in a different language

How do you know what patients want if you never even ask them?

Our mission at CIRM is to accelerate stem treatments to patients with unmet medical needs. But what if those needs are not just unmet, they’re also unknown? What happens when those developing treatments never even bother to ask those they are trying to help if this is what they really need, or want? The question … Continue reading How do you know what patients want if you never even ask them?

How to handle CRISPR: Formulating a responsible approach to gene-editing

In February 2016, CIRM sponsored a workshop to discuss the impact of CRISPR, a gene-editing tool that is transforming stem cell research. The workshop was designed to enable the Standards Working Group  (SWG) to reflect on policies governing the review and oversight of embryo research support by CIRM. After the workshop, we wrote a blog … Continue reading How to handle CRISPR: Formulating a responsible approach to gene-editing

Patients are the Heroes at the CIRM Alpha Stem Cell Clinics Symposium

UCSD’s Catriona Jamieson and patient advocate Sandra Dillon at the CIRM Alpha Clinic Network Symposium Sometimes, when you take a moment to stand back and look at what you have accomplished, you can surprise yourself at how far you have come, and how much you have done in a short space of time. Take the … Continue reading Patients are the Heroes at the CIRM Alpha Stem Cell Clinics Symposium

Rare disease underdogs come out on top at CIRM Board meeting

  It seems like an oxymoron but one in ten Americans has a rare disease. With more than 7,000 known rare diseases it’s easy to see how each one could affect thousands of individuals and still be considered a rare or orphan condition. Only 5% of rare diseases have FDA approved therapies People with rare … Continue reading Rare disease underdogs come out on top at CIRM Board meeting

A new way to make heart stem cells could potentially repair the damage of heart disease

Today we’re going to talk about heart failure. It’s a sobering topic given that over 20 million people world wide are currently suffering from this disease. Heart failure happens when the body’s heart can no longer pump blood effectively, which can lead to many nasty side effects and inevitably hastens death. Typical strategies for treating … Continue reading A new way to make heart stem cells could potentially repair the damage of heart disease

New stem cell approach targeting deadly blood cancers

Every four minutes someone in the US is diagnosed with a blood cancer. It might be lymphoma or leukemia, myeloma or myelodysplastic syndromes (MDS). While we have made great strides in treating some of these over the years, we still have a long way to go. Need proof? Well, every nine minutes someone in the US … Continue reading New stem cell approach targeting deadly blood cancers