DNA provides the code of life for nearly all living organisms. So, it’s no wonder that scientists have been studying DNA and the human genome (complete set of DNA) for decades. In April 1953, James Watson and Francis Crick, in collaboration with Rosalind Franklin, first described the structure of DNA as a double helix. In … Continue reading Celebrating National DNA Day Together
DNA
Scientists at USC untangle the mysteries of cellular reprogramming- a method that could be used to treat diseases
Dr. Justin Ichida, Assistant Professor at USC and lead author of the study Scientists have long tried to repurpose cells in order to potentially treat various types of conditions. This process, called reprogramming, involves changing one type of cell into another, such as a blood cell into a muscle cell or nerve cell. Although the … Continue reading Scientists at USC untangle the mysteries of cellular reprogramming- a method that could be used to treat diseases
“Junk” DNA is development gold for the dividing embryo
The DNA in our cells provide the instructions to make proteins, the workhorses of our body. Yet less than 2% of the 3 billion base pairs (the structural units of DNA) in each of our cells are actually involved in protein production. The rest, termed non-coding DNA for not being involved in protein production, has … Continue reading “Junk” DNA is development gold for the dividing embryo
Stem Cell Stories that Caught our Eye: finding the perfect match, imaging stem cells and understanding gene activity
Here are the stem cell stories that caught our eye this week. Enjoy! LAPD officer in search of the perfect match. This week, the San Diego Union-Tribune featured a story that tugs at your heart strings about an LAPD officer in desperate need of a bone marrow transplant. Matthew Medina is a 40-year-old man who was … Continue reading Stem Cell Stories that Caught our Eye: finding the perfect match, imaging stem cells and understanding gene activity
“Apples to Apples” analysis: induced pluripotent stem cell (iPSC) method doesn’t increase mutations
It’s full steam ahead for the development of induced pluripotent stem cell (iPSC)-derived clinical trials. That’s according to a group at the National Human Genome Research Institute in Bethesda, Maryland who report this week in PNAS that the process of reprogramming a skin cell into the embryonic stem cell-like state of an iPSC does not … Continue reading “Apples to Apples” analysis: induced pluripotent stem cell (iPSC) method doesn’t increase mutations
Stem cell stories that caught our eye: How Zika may impact adult brains; Move over CRISPR there’s a new kid in town; How our bodies store fat
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Zika virus could impact adult brains It’s not just a baby’s developing brain that is vulnerable to the Zika virus, adult brains may be too. … Continue reading Stem cell stories that caught our eye: How Zika may impact adult brains; Move over CRISPR there’s a new kid in town; How our bodies store fat
Salk scientists explain why brain cells are genetically diverse
Recent studies show why brain is genetically diverse, and neurons in the same brain can carry slightly different DNA blueprints. These differences may give neurons distinct functions. We can see this in genetically identical twins who sometimes grow less identical over time. Some develop different appearances. Others diverge in health, with one twin developing a … Continue reading Salk scientists explain why brain cells are genetically diverse
Timing is everything: could CRISPR gene editing push CIRM to change its rules on funding stem cell research?
Talk about timely. When we decided, several months ago, to hold a Standards Working Group (SWG) meeting to talk about the impact of CRISPR, a tool that is transforming the field of human gene editing, we had no idea that our meeting would fall smack in the midst of a flurry of news stories about … Continue reading Timing is everything: could CRISPR gene editing push CIRM to change its rules on funding stem cell research?
The key to unlocking stem cells’ potential and blocking a deadly threat
A small slice of who you are - brain cells made from embryonic stem cells. Our bodies are amazingly complex systems. Some estimates say there are more than 37 trillion cells in our bodies. That’s trillion with a “t”. Each of those cells communicates and signals with other cells, which makes our bodies one heck … Continue reading The key to unlocking stem cells’ potential and blocking a deadly threat
UCLA Scientists Find 3000 New Genes in “Junk DNA” of Immune Stem Cells
Genes and Junk Do you remember learning about Junk DNA when you took Biology in high school? The term was used to described 98% of the human genome that doesn’t make up its approximately 22,000 genes. We used to think that Junk DNA didn’t serve a purpose, but that was before we discovered special elements … Continue reading UCLA Scientists Find 3000 New Genes in “Junk DNA” of Immune Stem Cells