CIRM Manufacturing Network Symposium attendees. The California Institute for Regenerative Medicine (CIRM) is driving conversations and collaboration to address the manufacturing challenges of cell and gene therapies (CGT). CIRM hosted its inaugural Manufacturing Network Symposium in South San Francisco, bringing together more than 100 experts and stakeholders from the regenerative medicine field, including scientific leaders … Continue reading Tackling Cell and Gene Therapy Manufacturing Challenges
Author: Christina Smith
The Link Between Air Pollution and Autism
The California Institute for Regenerative Medicine (CIRM) is supporting innovative research into neuro diseases, including a project examining how air pollution may contribute to autism. Through the Research using Multidisciplinary, Innovative approaches in Neuro Diseases (ReMIND) program, Stuart Lipton, MD, PhD, and co-investigators Tomo Nakamura, PhD, John Yates, PhD, Marisa Roberto, PhD, and Nik Schork, … Continue reading The Link Between Air Pollution and Autism
Using Genetic Sequencing and AI to Identify and Treat Schizophrenia
Top left to right: Tomasz Nowakowski, PhD, and Nevan Krogan, PhD Bottom left to right: Aparna Bhaduri, PhD; Matt State, PhD; Alice Ting, PhD; Trey Ideker, PhD; Willow Coyote-Maestas, PhD A UC San Francisco research team funded by the California Institute for Regenerative Medicine (CIRM) is using genetic sequencing and AI to identify and treat … Continue reading Using Genetic Sequencing and AI to Identify and Treat Schizophrenia
How Discovery Research is Unlocking the DNA Behind Psychiatric Disorders
From top left to right: Xin Jin, PhD; Joseph Ecker, PhD; Rusty Gage, PhD Bottom left to right: Eran Mukamel, PhD and Maria Carol Marchetto, PhD As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our understanding of central nervous … Continue reading How Discovery Research is Unlocking the DNA Behind Psychiatric Disorders
Exploring Gene Therapy Treatments for Autism
Principal investigator Alex Pollen, PhD, with his co-investigators and team of researchers. A UC San Francisco–led research team, supported by a $12.2 million grant from the California Institute for Regenerative Medicine (CIRM), is exploring potential gene therapy for treatments autism as well as other neuropsychiatric disorders such as schizophrenia, and bipolar disorder. The project is … Continue reading Exploring Gene Therapy Treatments for Autism
CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism
From top left to right: Anne Bang, PhD; Carrie Bearden, PhD; Eugene Yeo, PhD; Jonathan Sebat, PhD Bottom left to right: Alysson Moutri, PhD; Lilia Iakoucheva, PhD; Sébastien Jacquemont; Trey Ideker, PhD A team of UC San Diego researchers with support of a $12.5 million grant from the California Institute for Regenerative Medicine (CIRM) plans … Continue reading CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism
The Stem Cellar’s Most Read Blogs of 2024
2024 was a significant year for the California Institute for Regenerative Medicine (CIRM). We reached major milestones, celebrated our 20th anniversary, and introduced our Strategic Allocation Framework (SAF) impact goals. We did this all while continuing to fund innovative work in regenerative medicine. The Stem Cellar blog is where we share these stories, providing readers … Continue reading The Stem Cellar’s Most Read Blogs of 2024
A Step Forward in the Fight Against Advanced Kidney Cancer
Photo Courtesy: Allogene Therapeutics Metastatic renal cell carcinoma (RCC) is an advanced kidney cancer with limited treatment options and a five‑year survival rate below 17%. With CIRM’s support, Allogene Therapeutics is developing ALLO‑316, an allogeneic CAR‑T cell therapy that targets CD70, a protein highly expressed on clear cell renal cell carcinoma (ccRCC) tumors. The approach … Continue reading A Step Forward in the Fight Against Advanced Kidney Cancer
UCLA researchers exploring ways to prevent heart failure after heart attacks
ENPP1 is expressed in the region of scarring after injury to the heart. Cardiac muscle shown in red and ENPP1 in green demonstrates expression of ENPP1 in the region of scar formation. | Credit: Arjun Deb Lab/UCLA At the California Institute for Regenerative Medicine (CIRM), we support cardiovascular research from Discovery through Clinical to advance … Continue reading UCLA researchers exploring ways to prevent heart failure after heart attacks
Elpida Therapeutics’ Study on Rare Nerve Disease CMT4J
CIRM awarded Elpida Therapeutics a $3.9 million grant in December 2023 to support a pioneering preclinical study on Charcot Marie Tooth disease type 4J (CMT4J).