How Discovery Research is Unlocking the DNA Behind Psychiatric Disorders

From top left to right: Xin Jin, PhD; Joseph Ecker, PhD; Rusty Gage, PhD Bottom left to right: Eran Mukamel, PhD and Maria Carol Marchetto, PhD As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our understanding of central nervous … Continue reading How Discovery Research is Unlocking the DNA Behind Psychiatric Disorders

Celebrating National DNA Day Together

DNA provides the code of life for nearly all living organisms. So, it’s no wonder that scientists have been studying DNA and the human genome (complete set of DNA) for decades. In April 1953, James Watson and Francis Crick, in collaboration with Rosalind Franklin, first described the structure of DNA as a double helix. In … Continue reading Celebrating National DNA Day Together

Scientists at USC untangle the mysteries of cellular reprogramming- a method that could be used to treat diseases

Dr. Justin Ichida, Assistant Professor at USC and lead author of the study Scientists have long tried to repurpose cells in order to potentially treat various types of conditions. This process, called reprogramming, involves changing one type of cell into another, such as a blood cell into a muscle cell or nerve cell. Although the … Continue reading Scientists at USC untangle the mysteries of cellular reprogramming- a method that could be used to treat diseases

HIV eliminated from mice using CRISPR and LASER ART

Dr. Kamel Khalili In the United States alone, there are approximately 1.1 million people living with Human immunodeficiency virus (HIV), a virus that weakens the immune system by destroying important cells that fight off disease and infection. This number is much larger on a global scale, with 36.9 million people living with HIV as of … Continue reading HIV eliminated from mice using CRISPR and LASER ART

“Junk” DNA is development gold for the dividing embryo

The DNA in our cells provide the instructions to make proteins, the workhorses of our body. Yet less than 2% of the 3 billion base pairs (the structural units of DNA) in each of our cells are actually involved in protein production. The rest, termed non-coding DNA for not being involved in protein production, has … Continue reading “Junk” DNA is development gold for the dividing embryo

Stem Cell Roundup: New understanding of Huntington’s; how stem cells can double your DNA; and using “the Gary Oldman of cell types” to reverse aging

This week's roundup highlights how we are constantly finding out new and exciting ways that stem cells could help change the way we treat disease. Our Cool Stem Cell Image of the Week comes from our first story, about unlocking some of the secrets of Huntington's disease. It comes from the Laboratory of Stem Cell … Continue reading Stem Cell Roundup: New understanding of Huntington’s; how stem cells can double your DNA; and using “the Gary Oldman of cell types” to reverse aging

Stem Cell Stories that Caught our Eye: finding the perfect match, imaging stem cells and understanding gene activity

Here are the stem cell stories that caught our eye this week. Enjoy! LAPD officer in search of the perfect match. This week, the San Diego Union-Tribune featured a story that tugs at your heart strings about an LAPD officer in desperate need of a bone marrow transplant. Matthew Medina is a 40-year-old man who was … Continue reading Stem Cell Stories that Caught our Eye: finding the perfect match, imaging stem cells and understanding gene activity

Stem Cell Stories That Caught Our Eye: Free Patient Advocate Event in San Diego, and new clues on how to fix muscular dystrophy and Huntington’s disease

Stem cell research is advancing so fast that it’s sometimes hard to keep up. That’s one of the reasons we have our Friday roundup, to let you know about some fascinating research that came across our desk during the week that you might otherwise have missed. Of course, another way to keep up with the … Continue reading Stem Cell Stories That Caught Our Eye: Free Patient Advocate Event in San Diego, and new clues on how to fix muscular dystrophy and Huntington’s disease

Stem cell stories that caught our eye: How Zika may impact adult brains; Move over CRISPR there’s a new kid in town; How our bodies store fat

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Zika virus could impact adult brains It’s not just a baby’s developing brain that is vulnerable to the Zika virus, adult brains may be too. … Continue reading Stem cell stories that caught our eye: How Zika may impact adult brains; Move over CRISPR there’s a new kid in town; How our bodies store fat

Salk scientists explain why brain cells are genetically diverse

I’ve always wondered why some sets of genetically identical twins become not so identical later in life. Sometimes they differ in appearance. Other times, one twin is healthy while the other is plagued with a serious disease. These differences can be explained by exposure to different environmental factors over time, but there could also be … Continue reading Salk scientists explain why brain cells are genetically diverse