An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration

We’ve written many blogs over the years about research focused on muscle stem cell function . Those stories describe how satellite cells, another name for muscle stem cells, lay dormant but jump into action to grow new muscle cells in response to injury and damage. And when satellite function breaks down with aging as well as … Continue reading An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration

CIRM Bridges Student Researcher Discovers Mentoring is a Two-Way Street

Jasmine Carter is a CIRM Bridges Scholar a Sacramento State University. She currently is interning in the lab of Dr. Kyle Fink at UC Davis and her research focuses on developing induced neurons from skin cells to model neurological disorders and develop novel therapeutics. Jasmine was a mentor to one of our UC Davis CIRM … Continue reading CIRM Bridges Student Researcher Discovers Mentoring is a Two-Way Street

How a funny-looking creature could unlock the secrets of limb regeneration

In the world of funny-looking creatures, the Axolotl would have to rank in the top ten alongside such notables as the naked mole rat and the blob fish (the official mascot for the Ugly Animal Preservation Society). But the Axolotl does have one attribute that makes it attractive to more than just another Axolotl. That’s … Continue reading How a funny-looking creature could unlock the secrets of limb regeneration

Stem Cell Stories That Caught Our Eye: Halting Brain Cancer, Parkinson’s disease and Stem Cell Awareness Day

Stopping brain cancer in its tracks. Scientists at Stanford Medicine discovered that you can halt aggressive brain cancers called high-grade gliomas by cutting off their supply of a signaling protein called neuroligin-3. Their research, which was funded by CIRM and the NIH, was published this week in the journal Nature.  The Stanford team, led by … Continue reading Stem Cell Stories That Caught Our Eye: Halting Brain Cancer, Parkinson’s disease and Stem Cell Awareness Day

Bioengineers make breathtaking step toward building a lung

Tissue engineers have made amazing progress when it comes to using stem cells to build tissues such as blood vessels, which have relatively simple tubular shape. In fact, a late stage CIRM-funded clinical trial run by Humacyte is testing an engineered vein to improve dialysis treatment for people with kidney disease. Building a lung that … Continue reading Bioengineers make breathtaking step toward building a lung

UCLA scientists begin a journey to restore the sense of touch in paralyzed patients

Yesterday, CIRM-funded scientists at UCLA published an interesting study that sheds light on the development of sensory neurons, a type of nerve cell that is damaged in patients with spinal cord injury. Their early-stage findings could potentially, down the road, lead to the development of stem cell-based treatments that rebuild the sensory nervous system in … Continue reading UCLA scientists begin a journey to restore the sense of touch in paralyzed patients

A trip to the OR started CIRM’s latest Board member on a career in science

The CIRM Board is pretty big, 29 members, all of whom have very different backgrounds and experiences. That’s one of its strengths, the diversity of members and the sheer range of expertise they bring to this work. Our newest member, Dr. David Martin, is the Chair and CEO of AvidBiotics Corp., a biotech company in … Continue reading A trip to the OR started CIRM’s latest Board member on a career in science

Blocking spike in stem cell growth after brain injury may lessen memory decline, seizures

Survivors of traumatic brain injury (TBI) often suffer from debilitating, life changing symptoms like memory decline and epileptic seizures. Researchers had observed that following TBI, a stem cell-rich area of the brain provides a spike in new nerve cell growth, presumably to help replace damaged or destroyed brain cells. But, like a lot of things … Continue reading Blocking spike in stem cell growth after brain injury may lessen memory decline, seizures

Stem Cell Stories That Caught our Eye: Insights into a healthy brain, targeting mutant cancers and commercializing cell therapies

Here's your weekly roundup of interesting stem cell stories! Partnership for a healthy brain. To differentiate or not to differentiate. That is the question the stem cells in our tissues and organs face. In the case of the brain, neural precursor cells can either remain in a stem cell state or they can differentiate into mature brain … Continue reading Stem Cell Stories That Caught our Eye: Insights into a healthy brain, targeting mutant cancers and commercializing cell therapies

Attractive new regenerative medicine tool uses magnets to shape and stimulate stem cells

The ultimate goal of tissue engineers who work in the regenerative medicine field is to replace damaged or diseased organs with new ones built from stem cells. To accomplish the feat, these researchers are developing new tools and techniques to manipulate and specialize stem cells into three dimensional structures. Some popular methods – which we’ve … Continue reading Attractive new regenerative medicine tool uses magnets to shape and stimulate stem cells