A single protein can boost blood stem cell regeneration

Today, CIRM-funded scientists from the UCLA Broad Stem Cell Research Center reported  in Nature Medicine that hematopoietic stem cells (HSCs) - blood stem cells that generate the cell in your blood and immune system - get a helping hand after injury from cells in the bone marrow called bone progenitor cells. By secreting a protein called dickkopf-1 … Continue reading A single protein can boost blood stem cell regeneration

Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart

Horsing around at the World Stem Cell Summit The World Stem Cell Summit (WSCS) is coming up very shortly (December 6-9) in lovely downtown West Palm Beach, Florida. And this year it has an added attraction; horses. For my money the WSCS is the most enjoyable of the many conferences held around the US focusing … Continue reading Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart

Stem cell agency funds clinical trials in three life-threatening conditions

A year ago the CIRM Board unanimously approved a new Strategic Plan for the stem cell agency. In the plan are some rather ambitious goals, including funding ten new clinical trials in 2016. For much of the last year that has looked very ambitious indeed. But today the Board took a big step towards reaching … Continue reading Stem cell agency funds clinical trials in three life-threatening conditions

Deleting a single gene can boost blood stem cell regeneration

A serious side effect that cancer patients undergoing chemotherapy experience is myelosuppression. That’s a big word for a process that involves the decreased production of the body’s immune cells from hematopoietic stem cells (HSCs) or blood stem cells in the bone marrow. Without these important cells that make up the immune system, patients are at … Continue reading Deleting a single gene can boost blood stem cell regeneration

Investing in student researchers now for future stem cell therapy homeruns

Even though my San Francisco Giants didn’t make it to the World Series this year, I still watched Game 1 two nights ago between the Cleveland Indians and the Chicago Cubs. As each batter stepped up to the plate for their first at bat, I thought about all the years of training and in-game experience … Continue reading Investing in student researchers now for future stem cell therapy homeruns

Stem cell stories that caught our eye: 3D mini-lungs, Parkinson’s culprit, Motherless babies!

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Mimicking human air sacs –  a new lab tool for studying respiratory disease Studying a flat lawn of cells in a petri dish is so … Continue reading Stem cell stories that caught our eye: 3D mini-lungs, Parkinson’s culprit, Motherless babies!

Stem cell stories that caught our eye: improving heart care, fixing sickle cell disease, stem cells & sugar

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Using “disease in a dish” model to improve heart care Medications we take to improve our quality of life might actually be putting our lives … Continue reading Stem cell stories that caught our eye: improving heart care, fixing sickle cell disease, stem cells & sugar

Stem cells maturing into nerve produce a compound that speeds the process

Getting pluripotent stem cells—those early stage stem cells that can make any tissue—to actually make the cell type you want can be quite tricky. I have written before that it takes a village to raise a stem cell because they respond to everything around them from the physical pressure and rigidity of their environment to … Continue reading Stem cells maturing into nerve produce a compound that speeds the process

Multi-Talented Stem Cells: The Many Ways to Use Them in the Clinic

CIRM kicked off the 2016 International Society for Stem Cell Research (ISSCR) Conference in San Francisco with a public stem cell event yesterday that brought scientists, patients, patient advocates and members of the general public together to discuss the many ways stem cells are being used in the clinic to develop treatments for patients with … Continue reading Multi-Talented Stem Cells: The Many Ways to Use Them in the Clinic

In the Stem Cellar: making better blood stem cells, a heart guard, iPS model points to ALS drug and tracking cells

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Major step in creating blood stem cells. If you track stem cells in any online news search, your feed perpetually will have numerous posts about … Continue reading In the Stem Cellar: making better blood stem cells, a heart guard, iPS model points to ALS drug and tracking cells