Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk

The good news is you’re cancer free, the bad news is you need a heart transplant. It almost sounds like the punchline to a joke, but it’s no laugher matter because the scenario is real for some cancer patients.  Chemotherapy is a life saver for many but certain doses can be so toxic that it’s often hard … Continue reading Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk

New study says stem cells derived from older people may have more problems than we thought.

Ever since 2006 when Japanese researcher Shinya Yamanaka showed that you could take an adult cell, such as those in your skin, and reprogram it to act like an embryonic stem cell, the scientific world has looked at these induced pluripotent stem (iPS) cells as a potential game changer. They had the ability to convert … Continue reading New study says stem cells derived from older people may have more problems than we thought.

Stem cells provide promising skin in the game for treating burn victims

For severe burn victims and others in need of skin transplants, current treatments using artificial skin grafts made from sheets of lab-grown skin cells aren’t ideal because they lack the complex structures needed to fully restore many of the skin’s critical functions. For example, artificial skin doesn’t contain oil-producing sebaceous glands and forces burn victims … Continue reading Stem cells provide promising skin in the game for treating burn victims

UCSF Scientists find molecular link between brain stem cells and Zika Infection

The Zika virus scare came to a head in 2015, prompting the World Health Organization to declare the outbreak a global health emergency earlier this year. From a research standpoint, much of the effort has centered on understanding whether the Zika infection is actually a cause of birth defects like microcephaly and how the virus … Continue reading UCSF Scientists find molecular link between brain stem cells and Zika Infection

Getting On Tract: Stem Cells Regenerate Injured Spinal Cord in Rats

The spinal cord acts as a highway that transports electrical signals from your brain to the rest of your body through long bundles of nerve fibers. It allows your brain to communicate with the rest of your body to coordinate movement and reflexes and to receive sensory information. When the spinal cord is damaged, the … Continue reading Getting On Tract: Stem Cells Regenerate Injured Spinal Cord in Rats

How do you know what patients want if you never even ask them?

Our mission at CIRM is to accelerate stem treatments to patients with unmet medical needs. But what if those needs are not just unmet, they’re also unknown? What happens when those developing treatments never even bother to ask those they are trying to help if this is what they really need, or want? The question … Continue reading How do you know what patients want if you never even ask them?

How to handle CRISPR: Formulating a responsible approach to gene-editing

In February 2016, CIRM sponsored a workshop to discuss the impact of CRISPR, a gene-editing tool that is transforming stem cell research. The workshop was designed to enable the Standards Working Group  (SWG) to reflect on policies governing the review and oversight of embryo research support by CIRM. After the workshop, we wrote a blog … Continue reading How to handle CRISPR: Formulating a responsible approach to gene-editing

Breast cancer: Piecing together early detection and treatment

Developing therapies for disease is kind of like trying to put together a series of incredibly complex puzzles. Scientists collect lots of “puzzle pieces”, in the form of data, through experiments in the lab and clinic or by reading up on other researchers’ results. Each piece gives researchers a tidbit of insight but the breakthroughs … Continue reading Breast cancer: Piecing together early detection and treatment

In the Race to Cure Blindness, Who Will Cross the Finish Line First Optogenetics or Stem Cells?

Before you read this blog, I wanted to share a photo that I took (yes with my iPhone 6…) last week of a beautiful sunset at Ocean Beach in San Francisco. I’m showing you this picture not to gloat that I live by the ocean, but to make a point. You’re able to enjoy this … Continue reading In the Race to Cure Blindness, Who Will Cross the Finish Line First Optogenetics or Stem Cells?

Patients are the Heroes at the CIRM Alpha Stem Cell Clinics Symposium

UCSD’s Catriona Jamieson and patient advocate Sandra Dillon at the CIRM Alpha Clinic Network Symposium Sometimes, when you take a moment to stand back and look at what you have accomplished, you can surprise yourself at how far you have come, and how much you have done in a short space of time. Take the … Continue reading Patients are the Heroes at the CIRM Alpha Stem Cell Clinics Symposium