Today the stem cell field got a double dose of good news. Two CIRM-funded studies from the Gladstone Institutes reported successfully reprogramming human skin into heart cells and brain cells in a dish using different cocktails of small molecule drugs. The work was led by Dr. Sheng Ding, a Senior Investigator at the Gladstone Institutes. … Continue reading Double dose of good news: scientists use drugs to turn skin into heart and brain cells
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UCSF study explains how chronic inflammation impairs blood stem cell function
Inflammation is the immune system’s natural protective response to infection and injury. It involves the activation and mobilization of immune cells that can kill off foreign invaders and help repair damaged tissue. At the heart of the inflammatory response are hematopoietic stem cells (HSCs). These are blood stem cells found in the bone marrow that … Continue reading UCSF study explains how chronic inflammation impairs blood stem cell function
A visual guide on using stem cells to treat blindness
Some stories are so sweet or powerful or wonderful - or all three - that they just stick in your mind. About 18 months ago Rosalinda and German Barrero came to talk to the CIRM Board about retinitis pigmentosa (RP), a devastating genetic disease that slowly destroys a person’s vision. Contrary to what everyone expected … Continue reading A visual guide on using stem cells to treat blindness
Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development
The great inventions – like the automobile, the Internet or aviation – are marked as important turning points in human history. But it’s usually the additional tinkering that goes on in the ensuing years after the initial invention that makes the technology feasible in terms of cost, reproducibility and mass production. The same holds true … Continue reading Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development
Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk
The good news is you’re cancer free, the bad news is you need a heart transplant. It almost sounds like the punchline to a joke, but it’s no laugher matter because the scenario is real for some cancer patients. Chemotherapy is a life saver for many but certain doses can be so toxic that it’s often hard … Continue reading Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk
New study says stem cells derived from older people may have more problems than we thought.
Ever since 2006 when Japanese researcher Shinya Yamanaka showed that you could take an adult cell, such as those in your skin, and reprogram it to act like an embryonic stem cell, the scientific world has looked at these induced pluripotent stem (iPS) cells as a potential game changer. They had the ability to convert … Continue reading New study says stem cells derived from older people may have more problems than we thought.
Diabetes’ demise? Master Switch Identified for Turning Stem Cells into Functional Insulin-Producing Cells
It’s been a good week for diabetes researchers and the over one million Americans with type 1 diabetes who are hoping for an eventual stem cell-based treatment for this incurable disease. Published a day apart, two studies reported on achieving an elusive goal for the field: creating functional insulin-producing cells in a lab dish from induced … Continue reading Diabetes’ demise? Master Switch Identified for Turning Stem Cells into Functional Insulin-Producing Cells
Good news for the Tin Man: Pig heart transplants work in baboons for 2+ years
If I only had a heart… My favorite character in the Wizard of Oz was the Tin Man because of the scene where he cries and starts to rust, causing Dorothy to rush to his aid with an oil can. He is such a tender heap of metal that just needs a heart to be … Continue reading Good news for the Tin Man: Pig heart transplants work in baboons for 2+ years
UCSF Scientists find molecular link between brain stem cells and Zika Infection
The Zika virus scare came to a head in 2015, prompting the World Health Organization to declare the outbreak a global health emergency earlier this year. From a research standpoint, much of the effort has centered on understanding whether the Zika infection is actually a cause of birth defects like microcephaly and how the virus … Continue reading UCSF Scientists find molecular link between brain stem cells and Zika Infection
Getting On Tract: Stem Cells Regenerate Injured Spinal Cord in Rats
The spinal cord acts as a highway that transports electrical signals from your brain to the rest of your body through long bundles of nerve fibers. It allows your brain to communicate with the rest of your body to coordinate movement and reflexes and to receive sensory information. When the spinal cord is damaged, the … Continue reading Getting On Tract: Stem Cells Regenerate Injured Spinal Cord in Rats
The Stem Cellar 