A Phase 1 clinical trial co-sponsored by CIRM and Oncternal Therapeutics, has started treating patients at UC San Diego (UCSD). The goal of the trial is to test the safety and anti-tumor activity of the Oncternal-developed drug, cirmtuzumab, in treating breast cancer. Breast cancer is the second most common cancer to occur in women, regardless … Continue reading A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer
Disease Areas
Deep dive into muscle repair yields new strategies to combat Duchenne muscular dystrophy
Researchers at the Sanford Burnham Prebys Medical Discovery Institute (SBP) reported new findings this week that may lead to novel therapeutic strategies for people suffering from Duchenne muscular dystrophy (DMD). DMD, a muscle-wasting disease that affects 1 in 7250 males aged 5 to 24 years in the United States, is caused by a genetic mutation leading … Continue reading Deep dive into muscle repair yields new strategies to combat Duchenne muscular dystrophy
Support cells have different roles in blood stem cell maintenance before and after stress
A new study published in the journal Cell Stem Cell, reveals how different types of cells in the bone marrow are responsible for supporting blood stem cell maintenance before and after injury. It was already well known in the field that two different cell types, namely endothelial cells (which line blood vessels) and stromal cells … Continue reading Support cells have different roles in blood stem cell maintenance before and after stress
Saying goodbye to a good friend and a stem cell pioneer: Karl Trede
Sometimes even courage and determination are not enough. Karl Trede had courage and determination in droves as he fought a 12 year battle against cancer. He recently lost that battle. But he remains an inspiration for all who knew him. I got to know Karl for our 2016 Annual Report. Karl had been diagnosed with … Continue reading Saying goodbye to a good friend and a stem cell pioneer: Karl Trede
A stepping stone for bringing stem cell therapy to patients with ALS
Imagine being told that you have a condition that gradually causes you to lose the ability to control your body movements, from picking up a pencil to walking to even breathing. Such is the reality for the nearly 6,000 people who are diagnosed with amyotrophic lateral sclerosis (ALS) every year, in the United States alone. … Continue reading A stepping stone for bringing stem cell therapy to patients with ALS
Join us tomorrow at noon for “Ask the Stem Cell Team about Sickle Cell Disease”, a FaceBook Live Event
As an early kick off to National Sickle Cell Awareness Month – which falls in September every year – CIRM is hosting a “Ask the Stem Cell Team” FaceBook Live event tomorrow, August 28th, from noon to 1pm (PDT). The live broadcast will feature two scientists and a patient advocate who are working hard to … Continue reading Join us tomorrow at noon for “Ask the Stem Cell Team about Sickle Cell Disease”, a FaceBook Live Event
Stem cell stories that caught our eye: CIRM-funded scientist wins prestigious prize and a tooth trifecta
CIRM-grantee wins prestigious research award Do we know how to pick ‘em or what? For a number of years now we have been funding the work of Stanford’s Dr. Marius Wernig, who is doing groundbreaking work in helping advance stem cell research. Just how groundbreaking was emphasized this week when he was named as the … Continue reading Stem cell stories that caught our eye: CIRM-funded scientist wins prestigious prize and a tooth trifecta
3D printed neuronal networks are an important step forward in treating spinal cord injury
Approximately 300,000 people in the United States live with spinal cord injury (SCI), and 17,000 new cases are reported every year. With no cure, the primary treatment option for people with SCI is rehabilitation with a physical therapist combined with medications to control the pain. Given the relatively permanent nature of these injuries, a new … Continue reading 3D printed neuronal networks are an important step forward in treating spinal cord injury
Stem cell stories that caught our eye: 3 blind mice no more and a tale of two tails
Stem cell image of the week: The demise of Three Blind Mice nursery rhyme (Todd Dubnicoff) Our stem cell image of the week may mark the beginning of the end of the Three Blind Mice nursery rhyme and, more importantly, usher in a new treatment strategy for people suffering from vision loss. That’s because researchers … Continue reading Stem cell stories that caught our eye: 3 blind mice no more and a tale of two tails
Regenerative Medicine by the numbers: a snapshot of how the field is progressing
Statistics don’t usually make for very exciting blog fodder, but they can be useful in charting progress. Case in point, the recent quarterly report from the Alliance for Regenerative Medicine (ARM), a global advocate and industry group for the field. In the report ARM takes an in-depth look at cell therapy, gene therapy, tissue engineering … Continue reading Regenerative Medicine by the numbers: a snapshot of how the field is progressing
The Stem Cellar 