THIS BLOT IS ALSO AVAILABLE AS AN AUDIOCAST ON SPOTIFY A National Institutes of Allergy and Infectious Diseases clinical trial admissions coordinator collects information from a volunteer to create a medical record. Credit: NIAID Alzheimer’s research has been in the news a lot lately, and not for the right reasons. The controversial decision by the … Continue reading Lack of diversity impacts research into Alzheimer’s and dementia
Liver Disease
Retooling a COVID drug to boost its effectiveness
Coronavirus particles, illustration. When the COVID-19 pandemic broke out scientists scrambled to find existing medications that might help counter the life-threatening elements of the virus. One of the first medications that showed real promise was remdesivir. It’s an anti-viral drug that was originally developed to target novel, emerging viruses, viruses like COVID19. It was approved … Continue reading Retooling a COVID drug to boost its effectiveness
New technique maps out diversity and location of cells in tissue or tumor
Image Description: Alex Marson is part of a team of researchers who developed a new technique to map the specialized diversity and spatial location of individual cells within a tissue or tumor. Photo Credit: Anastasiia Sapon All the cells in your body work together and each can have a different role. Their individual function not … Continue reading New technique maps out diversity and location of cells in tissue or tumor
Stem Cell All-Stars, All For You
Dr. Larry Goldstein, UC San Diego It’s not often you get a chance to hear some of the brightest minds around talk about their stem cell research and what it could mean for you, me and everyone else. That’s why we’re delighted to be bringing some of the sharpest tools in the stem cell shed … Continue reading Stem Cell All-Stars, All For You
Perseverance: from theory to therapy. Our story over the last year – and a half
Some of the stars of our Annual Report It’s been a long time coming. Eighteen months to be precise. Which is a peculiarly long time for an Annual Report. The world is certainly a very different place today than when we started, and yet our core mission hasn’t changed at all, except to spring into … Continue reading Perseverance: from theory to therapy. Our story over the last year – and a half
“Mini” human liver made of stem cells successfully transplanted in rats
Miniature liver made from human skin cells turned stem cells turned specialized liver cells Photo Credit: University of Pittsburgh School of Medicine According to the American Liver Foundation website, almost 14,000 patients are on the waiting list for a liver transplant. But what if there was a way to generate a liver using your own … Continue reading “Mini” human liver made of stem cells successfully transplanted in rats
CIRM invests $1.3 million to study stem cells in metabolic liver disease
Metabolic liver disease, is an emerging public health concern in Western countries, but has largely been overshadowed by health issues such as cancer and diabetes. Chronic liver disease (of which metabolic liver disease is a significant contributor) however, is a significant public health concern, evidenced by its contribution to nearly 2 million deaths per year … Continue reading CIRM invests $1.3 million to study stem cells in metabolic liver disease
Making stem cell-derived liver cells to study fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) affects approximately 30% of the population, with that number increasing to 75% in obese individuals. Shockingly, the number of cases is expected to increase 21% by the year 2030 in the United States alone. NAFLD refers to a broad range of liver conditions, which are all characterized by abnormally high … Continue reading Making stem cell-derived liver cells to study fatty liver disease
Livers skip stem cells, build missing structures from scratch via direct cell identity conversion
Stem cells…eh, who needs them anyway?! That’s what you might be thinking after today, at least for some forms of liver disease. That’s because a team of researchers from UCSF and Cincinnati Children’s Hospital Medical Center just published results in Nature showing liver cells can directly change identity, or transdifferentiate, in order to build, from … Continue reading Livers skip stem cells, build missing structures from scratch via direct cell identity conversion
East Coast Company to Sell Research Products Derived from CIRM’s Stem Cell Bank
With patient-derived induced pluripotent stem cells (iPSCs) in hand, any lab scientist can follow recipes that convert these embryonic-like stem cells into specific cell types for studying human disease in a petri dish. iPSCs derived from a small skin sample from a Alzheimer’s patient, for instance, can be specialized into neurons – the kind of … Continue reading East Coast Company to Sell Research Products Derived from CIRM’s Stem Cell Bank
The Stem Cellar 