Welcome back to our “Throwback Thursday” series on the Stem Cellar. Over the years, we’ve accumulated an arsenal of valuable stem cell stories on our blog. Some of these stories represent crucial advances towards stem cell-based cures for serious diseases and deserve a second look. This week in honor of Diabetes Awareness Month, we are … Continue reading Throwback Thursday: Progress to a Cure for Type 1 Diabetes
Diabetes
From Pig Parts to Stem Cells: Scientist Douglas Melton Wins Ogawa-Yamanaka Prize for Work on Diabetes
Since the 1920s, insulin injections have remained the best solution for managing type 1 diabetes. Patients with this disease do not make enough insulin – a hormone that regulates the sugar levels in your blood – because the insulin-producing cells, or beta cells, in their pancreas are destroyed. Back then, it took two tons of … Continue reading From Pig Parts to Stem Cells: Scientist Douglas Melton Wins Ogawa-Yamanaka Prize for Work on Diabetes
Stem cell stories that caught our eye: healing diabetic ulcers, new spinal cord injury insights & an expanding CRISPR toolbox
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Stem cells heal diabetic foot ulcers in pilot study Foot ulcers are one of the many long-term complications that diabetics face. About 15 percent of … Continue reading Stem cell stories that caught our eye: healing diabetic ulcers, new spinal cord injury insights & an expanding CRISPR toolbox
Faulty fat stem cells & obesity-related diabetes
You see it in the news all the time: more and more people around the world are obese and as a result they’re at a higher risk for diabetes, heart disease and cancer. In fact, 90% of individuals with type 2 diabetes are overweight or obese. “Healthy” obese individuals protected from diabetes and other complications … Continue reading Faulty fat stem cells & obesity-related diabetes
Beige isn’t bland when it comes to solving the obesity epidemic
Americans spend over $60 billion a year to lose weight and yet two-thirds (that’s more than 200 million) are considered overweight or obese. Losing weight should be easy: just eat less and exercise more, right? But our body’s metabolism is a very complex thing and appears to fight against our best efforts to shed pounds. … Continue reading Beige isn’t bland when it comes to solving the obesity epidemic
CIRM Board targets diabetes and kidney disease with big stem cell research awards
A recent study estimated there may be more than 500 million people worldwide who have diabetes. That’s an astounding figure and makes diabetes one of the largest chronic disease epidemics in human history. One of the most serious consequences of untreated or uncontrolled diabetes is kidney damage. That can lead to fatigue, weakness, confusion, kidney … Continue reading CIRM Board targets diabetes and kidney disease with big stem cell research awards
Scientists Make Insulin-Secreting Cells from Stem Cells of Type 1 Diabetes Patients
Stem cell research for diabetes is in a Golden Age. In the past few years, scientists have developed methods to generate insulin-secreting pancreatic beta cell-like cells from embryonic stem cells, induced pluripotent stem cells (iPS cells), and even directly from human skin. We’ve covered a number of recent studies in this area on our blog, … Continue reading Scientists Make Insulin-Secreting Cells from Stem Cells of Type 1 Diabetes Patients
Diabetes’ demise? Master Switch Identified for Turning Stem Cells into Functional Insulin-Producing Cells
It’s been a good week for diabetes researchers and the over one million Americans with type 1 diabetes who are hoping for an eventual stem cell-based treatment for this incurable disease. Published a day apart, two studies reported on achieving an elusive goal for the field: creating functional insulin-producing cells in a lab dish from induced … Continue reading Diabetes’ demise? Master Switch Identified for Turning Stem Cells into Functional Insulin-Producing Cells
Stem cells from “love-handles” could help diabetes patients
Love handles usually get a bad rap, but this week, a study from Switzerland claims that stem cells taken from the fat tissue of “love handles” could one day benefit diabetes patients. The study, which was published in Nature Communications, generated the much coveted insulin-secreting pancreatic beta cells from human induced pluripotent stem cells (iPS … Continue reading Stem cells from “love-handles” could help diabetes patients
Stem cell stories that caught our eye: sexual identity of organs, upping the game of muscle stem cells, mini guts produce insulin
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. A new sexual identity crisis—in our organs. With the transition from Mr. to Ms. Jenner and other transsexual news this year, it seems inevitable that … Continue reading Stem cell stories that caught our eye: sexual identity of organs, upping the game of muscle stem cells, mini guts produce insulin