The Stem Cellar’s Image of the Week. Our favorite image this week, comes to us from researchers at Washington University School of Medicine in St. Louis. Looking like a psychedelic Rorschach test, the fluorescence microscopy depicts mouse olfactory epithelium (in green), a sheet of tissue that develops in the nose. The team identified a new … Continue reading Stem Cell Roundup: Knowing the nose, stem cell stress and cell fate math.
Autism
Friday Stem Cell Roundup: Making Nerves from Blood; New Clues to Treating Parkinson’s
Stanford lab develops method to make nerve cells from blood. Back in 2010, Stanford Professor Marius Wernig and his team devised a method to directly convert skin cells into neurons, a nerve cell. This so-called transdifferentiation technique leapfrogs over the need to first reprogram the skin cells into induced pluripotent stem cells. This breakthrough provided … Continue reading Friday Stem Cell Roundup: Making Nerves from Blood; New Clues to Treating Parkinson’s
East Coast Company to Sell Research Products Derived from CIRM’s Stem Cell Bank
With patient-derived induced pluripotent stem cells (iPSCs) in hand, any lab scientist can follow recipes that convert these embryonic-like stem cells into specific cell types for studying human disease in a petri dish. iPSCs derived from a small skin sample from a Alzheimer’s patient, for instance, can be specialized into neurons – the kind of … Continue reading East Coast Company to Sell Research Products Derived from CIRM’s Stem Cell Bank
Modeling the Human Brain in 3D
Can you guess what the tiny white balls are in this photo? I’ll give you a hint, they represent the organ that you’re using right now to answer my question. These are 3D brain organoids generated from human pluripotent stem cells growing in a culture dish. You can think of them as miniature models of … Continue reading Modeling the Human Brain in 3D
Stem cell-derived, 3D brain tissue reveals autism insights
Studying human brain disorders is one of the most challenging fields in biomedical research. Besides the fact that the brain is incredibly complex, it’s just plain difficult to peer into it. For one thing, it’s not practical, let alone ethical, to drill into an affected person’s skull and collect brain cells to learn about their … Continue reading Stem cell-derived, 3D brain tissue reveals autism insights
CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia
Imagine you’ve just stopped your car at the top of the steepest street in San Francisco. Now, if want to stay at the top of the hill you’re going to need to keep your foot on the brakes. Let go and you’ll start rolling down. Fast. Conceptually, similar decision points happen in human development. A … Continue reading CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia
One scientist’s quest to understand autism using stem cells
April is National Autism Awareness Month and people and organizations around the world are raising awareness about a disorder that affects more than 20 million people globally. Autism affects early brain development and causes a wide spectrum of social, mental, physical and emotional symptoms that appear during childhood. Because the symptoms and their severity can … Continue reading One scientist’s quest to understand autism using stem cells
Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell transplants help put MS in remission: A combination of high dose immunosuppressive therapy and transplant of a person’s own blood stem cells seems to be a powerful tool in helping people with relapsing-remitting multiple sclerosis (RRMS) go into sustained remission. Multiple sclerosis (MS) is an autoimmune disorder where the body’s own immune system … Continue reading Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
CIRM Grantees Reflect on Ten Years of iPS Cells
For the fourth entry for our “Ten Years of Induced Pluripotent Stem (iPS) Cells” series, which we’ve been posting all month, I reached out to three of our CIRM grantees to get their perspectives on the impact of iPSC technology on their research and the regenerative medicine field as a whole: Step back in time … Continue reading CIRM Grantees Reflect on Ten Years of iPS Cells
Stem cell stories that caught our eye: herding stem cells, mini autistic brains, tendon repair and hair replacement
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Major advance in getting stem cells to behave. The promise of embryonic stem cells comes from their ability to become any cell type in the … Continue reading Stem cell stories that caught our eye: herding stem cells, mini autistic brains, tendon repair and hair replacement
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