CIRM Board approves first program eligible for co-funding under the agreement Adrienne Shapiro, co-founder of Axis Advocacy, with her daughter Marissa Cors, who has Sickle Cell Disease. Sickle Cell disease (SCD) is a painful, life-threatening blood disorder that affects around 100,000 people, mostly African Americans, in the US. Even with optimal medical care, SCD shortens … Continue reading CIRM & NHLBI Create Landmark Agreement on Curing Sickle Cell Disease
CRISPR
Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
Dr. Matthew Porteus, professor of pediatrics at Stanford University. Photo courtesy of Stanford Medicine. Our immune system is an important and essential part of everyday life. It is crucial for fighting off colds and, with the help of vaccinations, gives us immunity to potentially lethal diseases. Unfortunately, for some infants, this innate bodily defense mechanism … Continue reading Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Illustration courtesy of TED website There has been a lot of conversation surrounding CRISPR-Cas9 in these recent months as well as many sensational news stories. Some of these stories highlight the promise this technology holds, while others emphasize a word of caution. But what exactly does this technology do and how does it work? Here … Continue reading CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Midwest universities are making important tools to advance stem cell research
Two Midwest universities are making headlines for their contributions to stem cell research. Both are developing important tools to advance this field of study, but in two unique ways. Scientists at the University of Michigan (UM), have compiled an impressive repository of disease-specific stem cell lines. Cell lines are crucial tools for scientists to study … Continue reading Midwest universities are making important tools to advance stem cell research
Researcher claims to have made first gene-edited baby. But did it really happen?
Remember the Raelians? Probably not. But way back in 2002 the group, some described them as a cult, claimed it had created the world’s first cloned baby. The news made headlines all around the world raising fears we were stepping into uncharted scientific territory. Several weeks later the scientist brought in by the Raelians to … Continue reading Researcher claims to have made first gene-edited baby. But did it really happen?
New partnership to make CIRM supported treatment for type 1 diabetes even better
ViaCyte, a regenerative medicine company long backed by CIRM, announced a partnership with CRISPR Therapeutics to increase the number of people with Type 1 Diabetes (T1D) who could benefit from their PEC-Direct therapeutic implant. Last year, CIRM granted ViaCyte $20 million to facilitate development of PEC-Direct, a device that both transplants pancreatic progenitor stem … Continue reading New partnership to make CIRM supported treatment for type 1 diabetes even better
Has Regenerative Medicine Come of Age?
For the past few years the Signals blog site - which offers an insiders’ perspectives on the world of regenerative medicine and stem cell research - has hosted what it calls a "Blog Carnival". This is an event where bloggers from across the stem cell field are invited to submit a piece based on a … Continue reading Has Regenerative Medicine Come of Age?
CRISPR Gene Editing Tool Linked to Unexpected Collateral DNA Damage
CRISPR–Cas9 has been widely hailed as the gene editing tool of the future. But research, published in the journal Nature Biotechnology, about the effects of CRISPR/Cas9, have found it can cause unexpected genetic damage which could lead to dangerous changes in some cells. Scientists have also learned there may be some safety implications for … Continue reading CRISPR Gene Editing Tool Linked to Unexpected Collateral DNA Damage
The Stem Cellar 