Josh Lehrer, M.D., CEO of Graphite Bio This week saw the launch of the 45th startup company enabled by CIRM funding of translational research at California academic institutions. Graphite Bio officially launched with the help of $45M in funding led by bay area venture firms Versant Ventures and Samsara BioCapital to spinout a novel CRISPR … Continue reading Graphite Bio launches and will prepare for clinical trial based on CIRM-funded research
CRISPR
Building a progressive pipeline
Dr. Kelly Shepard By Dr. Kelly Shepard One of our favorite things to do at CIRM is deliver exciting news about CIRM projects. This usually entails discussion of recent discoveries that made headlines, or announcing the launch of a new CIRM-funded clinical trial …. tangible signs of progress towards addressing unmet medical needs through advances … Continue reading Building a progressive pipeline
Meet the people who are changing the future
Kristin MacDonald Every so often you hear a story and your first reaction is “oh, I have to share this with someone, anyone, everyone.” That’s what happened to me the other day. I was talking with Kristin MacDonald, an amazing woman, a fierce patient advocate and someone who took part in a CIRM-funded clinical trial … Continue reading Meet the people who are changing the future
Two studies identify a molecule that could be used to block Zika virus and kill cancer cells
Dr. Tariq Rana (left) and Dr. Jeremy Rich (right) both lead independent teams at UC San Diego that identified a molecule, αvβ5 integrin, as the Zika virus' key to getting into brain stem cells Zika virus is caused by a virus transmitted by Aedes mosquitoes. People usually develop mild symptoms that include fever, rash, and … Continue reading Two studies identify a molecule that could be used to block Zika virus and kill cancer cells
CIRM Board Awards $15.8 Million to Four Translational Research Projects
Last week, the CIRM Board approved $32.92 million in awards directed towards four new clinical trials in vision related diseases and Parkinson's Disease. In addition to these awards, the Board also approved investing $15.80 million in four awards in the Translational Research program. The goal of this program is to help promising projects complete the … Continue reading CIRM Board Awards $15.8 Million to Four Translational Research Projects
Stanford and University of Tokyo researchers crack the code for blood stem cells
Blood stem cells grown in lab Blood stem cells offer promise for a variety of immune and blood related disorders such as sickle cell disease and leukemia. Like other stem cells, blood stem cells have the ability to generate additional blood stem cells in a process called self-renewal. Additionally, they are able to generate blood … Continue reading Stanford and University of Tokyo researchers crack the code for blood stem cells
CIRM & NHLBI Create Landmark Agreement on Curing Sickle Cell Disease
CIRM Board approves first program eligible for co-funding under the agreement Adrienne Shapiro, co-founder of Axis Advocacy, with her daughter Marissa Cors, who has Sickle Cell Disease. Sickle Cell disease (SCD) is a painful, life-threatening blood disorder that affects around 100,000 people, mostly African Americans, in the US. Even with optimal medical care, SCD shortens … Continue reading CIRM & NHLBI Create Landmark Agreement on Curing Sickle Cell Disease
Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
Dr. Matthew Porteus, professor of pediatrics at Stanford University. Photo courtesy of Stanford Medicine. Our immune system is an important and essential part of everyday life. It is crucial for fighting off colds and, with the help of vaccinations, gives us immunity to potentially lethal diseases. Unfortunately, for some infants, this innate bodily defense mechanism … Continue reading Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Illustration courtesy of TED website There has been a lot of conversation surrounding CRISPR-Cas9 in these recent months as well as many sensational news stories. Some of these stories highlight the promise this technology holds, while others emphasize a word of caution. But what exactly does this technology do and how does it work? Here … Continue reading CRISPR-Cas9 101: an overview and the role it plays in developing therapies
Midwest universities are making important tools to advance stem cell research
Two Midwest universities are making headlines for their contributions to stem cell research. Both are developing important tools to advance this field of study, but in two unique ways. Scientists at the University of Michigan (UM), have compiled an impressive repository of disease-specific stem cell lines. Cell lines are crucial tools for scientists to study … Continue reading Midwest universities are making important tools to advance stem cell research