Stem cells offer new drug for blood diseases. A new treatment for blood disorders might be in the works thanks to a stem cell-based study out of Harvard Medical School and Boston Children’s hospital. Their study was published in the journal Science Translational Medicine. The teams made induced pluripotent stem cells (iPSCs) from the skin … Continue reading Stem Cell Stories That Caught our Eye: Making blood and muscle from stem cells and helping students realize their “pluripotential”
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“Apples to Apples” analysis: induced pluripotent stem cell (iPSC) method doesn’t increase mutations
It’s full steam ahead for the development of induced pluripotent stem cell (iPSC)-derived clinical trials. That’s according to a group at the National Human Genome Research Institute in Bethesda, Maryland who report this week in PNAS that the process of reprogramming a skin cell into the embryonic stem cell-like state of an iPSC does not … Continue reading “Apples to Apples” analysis: induced pluripotent stem cell (iPSC) method doesn’t increase mutations
Curing the Incurable through Definitive Medicine
“Curing the Incurable”. That was the theme for the first annual Center for Definitive and Curative Medicine (CDCM) Symposium held last week at Stanford University, in Palo Alto, California. The CDCM is a joint initiative amongst Stanford Healthcare, Stanford Children’s Health and the Stanford School of Medicine. Its mission is to foster an environment that … Continue reading Curing the Incurable through Definitive Medicine
Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell transplants help put MS in remission: A combination of high dose immunosuppressive therapy and transplant of a person’s own blood stem cells seems to be a powerful tool in helping people with relapsing-remitting multiple sclerosis (RRMS) go into sustained remission. Multiple sclerosis (MS) is an autoimmune disorder where the body’s own immune system … Continue reading Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Mini-guts made from stem cells uncover mechanisms of viral infection in infants
Besides their chubby cheeks and cute little toes, I think what makes newborns so precious is how vulnerable they are in those first few days and months of life. For instance, infants are particularly easy targets for infections of the gut caused by enteroviruses. While healthy adults infected with these viruses may exhibit mild cold … Continue reading Mini-guts made from stem cells uncover mechanisms of viral infection in infants
Let’s Be Clear: Stem Cells and Popular Culture
The following is a guest blog from Matt Donne, PhD. Thoughts expressed here are not necessarily those of CIRM. It was during winter break of my Junior year in college that the gap between the general public’s understanding of embryonic stem cell biology and the reality of that research quickly came into focus for me. … Continue reading Let’s Be Clear: Stem Cells and Popular Culture
Stem Cells Profiles in Courage: Frank’s final gift
Not every story has a happy ending. But they do all have something to teach us. In the case of Frank St. Clair the lesson was simple: live life fully and freely, love those around you, and never give up. We were fortunate enough to get to know Frank as one of the people we … Continue reading Stem Cells Profiles in Courage: Frank’s final gift
Stories that caught our eye: new target for killing leukemia cancer stem cells and stem cell vesicles halt glaucoma
New stem cell target for acute myeloid leukemia (Karen Ring). A new treatment for acute myeloid leukemia, a type of blood cancer that turns bone marrow stem cells cancerous, could be in the works in the form of a cancer stem cell destroying antibody. Scientists from the NYU Langone Medical Center and the Memorial Sloan … Continue reading Stories that caught our eye: new target for killing leukemia cancer stem cells and stem cell vesicles halt glaucoma
Growing a rat pancreas in a mouse with stem cells & CRISPR: a solution for the organ shortage crisis?
Right now, about 120,000 Americans are on a waiting list for an organ transplant and 22 will die today before any organs become available. The plain truth is there aren’t enough organ donors to meet the demand. And according to the U.S. Department of Health and Human Services, the number of available organ donors has … Continue reading Growing a rat pancreas in a mouse with stem cells & CRISPR: a solution for the organ shortage crisis?
Good news from Asterias’ CIRM-funded spinal cord injury trial
This week in the stem cell field, all eyes are on Asterias Biotherapeutics, a California-based company that’s testing a stem cell based-therapy in a CIRM-funded clinical trial for spinal cord injury patients. The company launched its Phase 1/2a clinical trial back in 2014 with the goal of determining the safety of the therapy and the … Continue reading Good news from Asterias’ CIRM-funded spinal cord injury trial