It seems like a contradiction in terms to say that there are nearly 7,000 diseases, affecting 30 million people, that are considered rare in the US. But the definition of a rare disease is one that affects fewer than 200,000 people and the National Institutes of Health’s (NIH) Genetic and Rare Diseases Information Center (GARD) … Continue reading Rare diseases are not so rare
Cell Type
Stem cell stories that caught our eye: drug safety for heart cells, worms hijack plant stem cells & battling esophageal cancer
Devising a drug safety measuring stick in stem cell-derived heart muscle cells One of the mantras in the drug development business is “fail early”. That’s because most of the costs of getting a therapy to market occur at the later stages when an experimental treatment is tested in clinical trials in people. So, it’s best … Continue reading Stem cell stories that caught our eye: drug safety for heart cells, worms hijack plant stem cells & battling esophageal cancer
Rhythmic brain circuits built from stem cells
The TV commercial is nearly 20 years old but I remember it vividly: a couple is driving down a street when they suddenly realize the music on their tape deck is in sync with the repetitive activity on the street. From the guy casually dribbling a basketball to people walking along the sidewalk to the … Continue reading Rhythmic brain circuits built from stem cells
Wishing You and Your Stem Cells a Happy Valentine’s Day!
Roses are Red, Violets are Blue, Let’s thank pluripotent stem cells, For making humans like me and you Happy Valentine’s Day from me and everyone at CIRM! Today, we are celebrating this day of love by sending our warmest wishes to you our readers. We’re grateful for your interest in learning more about stem cells … Continue reading Wishing You and Your Stem Cells a Happy Valentine’s Day!
Stem Cell Stories That Caught our Eye: Making blood and muscle from stem cells and helping students realize their “pluripotential”
Stem cells offer new drug for blood diseases. A new treatment for blood disorders might be in the works thanks to a stem cell-based study out of Harvard Medical School and Boston Children’s hospital. Their study was published in the journal Science Translational Medicine. The teams made induced pluripotent stem cells (iPSCs) from the skin … Continue reading Stem Cell Stories That Caught our Eye: Making blood and muscle from stem cells and helping students realize their “pluripotential”
“Apples to Apples” analysis: induced pluripotent stem cell (iPSC) method doesn’t increase mutations
It’s full steam ahead for the development of induced pluripotent stem cell (iPSC)-derived clinical trials. That’s according to a group at the National Human Genome Research Institute in Bethesda, Maryland who report this week in PNAS that the process of reprogramming a skin cell into the embryonic stem cell-like state of an iPSC does not … Continue reading “Apples to Apples” analysis: induced pluripotent stem cell (iPSC) method doesn’t increase mutations
Curing the Incurable through Definitive Medicine
“Curing the Incurable”. That was the theme for the first annual Center for Definitive and Curative Medicine (CDCM) Symposium held last week at Stanford University, in Palo Alto, California. The CDCM is a joint initiative amongst Stanford Healthcare, Stanford Children’s Health and the Stanford School of Medicine. Its mission is to foster an environment that … Continue reading Curing the Incurable through Definitive Medicine
Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell transplants help put MS in remission: A combination of high dose immunosuppressive therapy and transplant of a person’s own blood stem cells seems to be a powerful tool in helping people with relapsing-remitting multiple sclerosis (RRMS) go into sustained remission. Multiple sclerosis (MS) is an autoimmune disorder where the body’s own immune system … Continue reading Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Mini-guts made from stem cells uncover mechanisms of viral infection in infants
Besides their chubby cheeks and cute little toes, I think what makes newborns so precious is how vulnerable they are in those first few days and months of life. For instance, infants are particularly easy targets for infections of the gut caused by enteroviruses. While healthy adults infected with these viruses may exhibit mild cold … Continue reading Mini-guts made from stem cells uncover mechanisms of viral infection in infants
Let’s Be Clear: Stem Cells and Popular Culture
The following is a guest blog from Matt Donne, PhD. Thoughts expressed here are not necessarily those of CIRM. It was during winter break of my Junior year in college that the gap between the general public’s understanding of embryonic stem cell biology and the reality of that research quickly came into focus for me. … Continue reading Let’s Be Clear: Stem Cells and Popular Culture
The Stem Cellar 