This blog is part of our Month of CIRM series, which features our Agency’s progress towards achieving our mission to accelerate stem cell treatments to patients with unmet medical needs. This week, we’re highlighting CIRM-funded clinical trials to address the growing interest in our rapidly expanding clinical portfolio. Today we are featuring trials in our blood and … Continue reading CIRM-Funded Clinical Trials Targeting Blood and Immune Disorders
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CIRM-Funded Clinical Trials Targeting Cancers
Welcome to the Month of CIRM! As we mentioned in last Thursday’s blog, during the month of October we’ll be looking back at what CIRM has done since the agency was created by the people of California back in 2004. To start things off, we’ll be focusing on CIRM-funded clinical trials this week. Supporting clinical … Continue reading CIRM-Funded Clinical Trials Targeting Cancers
An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration
We’ve written many blogs over the years about research focused on muscle stem cell function . Those stories describe how satellite cells, another name for muscle stem cells, lay dormant but jump into action to grow new muscle cells in response to injury and damage. And when satellite function breaks down with aging as well as … Continue reading An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration
How a funny-looking creature could unlock the secrets of limb regeneration
In the world of funny-looking creatures, the Axolotl would have to rank in the top ten alongside such notables as the naked mole rat and the blob fish (the official mascot for the Ugly Animal Preservation Society). But the Axolotl does have one attribute that makes it attractive to more than just another Axolotl. That’s … Continue reading How a funny-looking creature could unlock the secrets of limb regeneration
Stem Cell Stories That Caught Our Eye: Halting Brain Cancer, Parkinson’s disease and Stem Cell Awareness Day
Stopping brain cancer in its tracks. Scientists at Stanford Medicine discovered that you can halt aggressive brain cancers called high-grade gliomas by cutting off their supply of a signaling protein called neuroligin-3. Their research, which was funded by CIRM and the NIH, was published this week in the journal Nature. The Stanford team, led by … Continue reading Stem Cell Stories That Caught Our Eye: Halting Brain Cancer, Parkinson’s disease and Stem Cell Awareness Day
Bioengineers make breathtaking step toward building a lung
Tissue engineers have made amazing progress when it comes to using stem cells to build tissues such as blood vessels, which have relatively simple tubular shape. In fact, a late stage CIRM-funded clinical trial run by Humacyte is testing an engineered vein to improve dialysis treatment for people with kidney disease. Building a lung that … Continue reading Bioengineers make breathtaking step toward building a lung
Blocking spike in stem cell growth after brain injury may lessen memory decline, seizures
Survivors of traumatic brain injury (TBI) often suffer from debilitating, life changing symptoms like memory decline and epileptic seizures. Researchers had observed that following TBI, a stem cell-rich area of the brain provides a spike in new nerve cell growth, presumably to help replace damaged or destroyed brain cells. But, like a lot of things … Continue reading Blocking spike in stem cell growth after brain injury may lessen memory decline, seizures
Attractive new regenerative medicine tool uses magnets to shape and stimulate stem cells
The ultimate goal of tissue engineers who work in the regenerative medicine field is to replace damaged or diseased organs with new ones built from stem cells. To accomplish the feat, these researchers are developing new tools and techniques to manipulate and specialize stem cells into three dimensional structures. Some popular methods – which we’ve … Continue reading Attractive new regenerative medicine tool uses magnets to shape and stimulate stem cells
Protein that turns normal cells into cancer stem cells offers target to fight colon cancer
Colon cancer is a global killer. Each year more than one million people worldwide are diagnosed with it; more than half a million die from it. If diagnosed early enough the standard treatment involves surgery, chemotherapy, radiation or targeted drug therapy to destroy the tumors. In many cases this may work. But in some cases, … Continue reading Protein that turns normal cells into cancer stem cells offers target to fight colon cancer
CIRM-funded scientists discover a new way to make stem cells using antibodies
Just as learning a new skill takes time to hone, scientific discoveries take time to perfect. Such is the case with induced pluripotent stem cells (iPSCs), the Nobel Prize winning technology that reprograms mature adult cells back into a pluripotent stem cell state. iPSCs are a powerful tool because they can develop into any cell … Continue reading CIRM-funded scientists discover a new way to make stem cells using antibodies