Some years ago I was in the Wren Library at Trinity College, Cambridge in England when I noticed a display case with a cloth over it. Being a naturally curious person, downright nosy in fact, I lifted the cloth. In the display case was a first edition of Sir Isaac Newton’s Principia Mathematica and in … Continue reading The best scientists always want to know more
Embryonic Stem Cells
CIRM-funded clinical trial for spinal cord injury reports promising results
Today, the Menlo Park-based biotech company Asterias Biotherapeutics reported positive results from the first three patients treated in its Phase 1/2a clinical study using stem cell therapy to treat patients with spinal cord injury. This trial is funded by a CIRM Strategic Partnerships Award grant of $14.3 million. Asterias has developed a stem cell therapy … Continue reading CIRM-funded clinical trial for spinal cord injury reports promising results
Stem cell stories that caught our eye: getting the right cell, an energy booster, history of controversy and a fun video
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Light used to direct stem cell fate. Stem cells respond to a symphony of cellular signals telling them to remain stem cells or to mature … Continue reading Stem cell stories that caught our eye: getting the right cell, an energy booster, history of controversy and a fun video
Study Identifies Safer Stem Cell Therapies
To reject or not reject, that is the question facing the human immune system when new tissue or cells are transplanted into the body. Stem cell-therapy promises hope for many debilitating diseases that currently have no cures. However, the issue of immune rejection has prompted scientists to carefully consider how to develop safe stem cell … Continue reading Study Identifies Safer Stem Cell Therapies
Specialized Embryonic Stem Cells Yield Insights into X Chromosome Inactivation
Please don’t be intimidated by the title of this post! By the end of this blog, you’ll be well versed in X chromosome inactivation, and you’ll understand why you should care about this topic. Males and females are different in countless ways, but the underlying cause of these differences originates with chromosomes. Women have two … Continue reading Specialized Embryonic Stem Cells Yield Insights into X Chromosome Inactivation
Earliest stem cells made in lab; provide “extraordinary” potential
Embryonic stem cells are classified as pluripotent cells because they are able (“potent”) to mature into almost every (“pluri”) cell type. Thanks to Nobel Prize winner Shinya Yamanaka, researchers have been able to reprogram fully matured cells, like skin or blood, into embryonic stem cell-like induced pluripotent stem cells (iPS). The technique has revolutionized stem … Continue reading Earliest stem cells made in lab; provide “extraordinary” potential
Going back to figure out how the embryo makes muscles led team to way to mass produce muscle fibers
Sometimes in science what seems like the simpler task turns out to be the hardest. We have written extensively about research teams building mini-organs in lab dishes turning stem cells into multiple layers of tissues organized and functioning, at least in part, like the kidney, liver or stomach they mimic. Given these successes and the … Continue reading Going back to figure out how the embryo makes muscles led team to way to mass produce muscle fibers
Building a Bridge to Therapies: Stem Cell-Derived Neurons Restore Feeling to Injured Limbs
It’s been a great week for spinal cord injury-related stem cell research – and it’s only Tuesday. In case you missed it, Asterias Biotherapeutics announced yesterday that they had treated their first clinical trial participant with an embryonic stem cell-based therapy for complete spinal cord injury. “Complete” refers to injuries that cause a total loss … Continue reading Building a Bridge to Therapies: Stem Cell-Derived Neurons Restore Feeling to Injured Limbs
Scientists Sink their Teeth into Stem Cell Evolution
Sometimes, answers to biology’s most important questions can be found in the most unexpected of places. As reported in the most recent issue of the journal Cell Reports, researchers at the University of California, San Francisco (UCSF) and the University of Helsinki describe how studying fossilized rodent teeth has helped them inch closer to grasping … Continue reading Scientists Sink their Teeth into Stem Cell Evolution
Molecular Trick Diminishes Appearance of Scars, Stanford Study Finds
Every scar tells a story, but that story may soon be coming to a close, as new research from Stanford University reveals clues to why scars form—and offers clues on how scarring could become a thing of the past. Reported last week in the journal Science, the research team pinpointed the type of skin cell … Continue reading Molecular Trick Diminishes Appearance of Scars, Stanford Study Finds
The Stem Cellar 