Here are the stem cell stories that caught our eye this week. Enjoy! Scientists claim first CRISPR editing of human embryos in the US. Here’s the big story this week. Scientists from Portland, Oregon claim they genetically modified human embryos using the CRISPR/Cas9 gene editing technology. While their results have yet to be published in … Continue reading Stem Cell Stories that Caught our Eye: CRISPRing Human Embryos, brain stem cells slow aging & BrainStorm ALS trial joins CIRM Alpha Clinics
Brain stem cells
Harnessing DNA as a programmable instruction kit for stem cell function
DNA is the fundamental molecule to all living things. The genetic sequences embedded in its double-helical structure contain the instructions for producing proteins, the building blocks of our cells. When our cells divide, DNA readily unzips into two strands and makes a copy of itself for each new daughter cell. In a Nature Communications report … Continue reading Harnessing DNA as a programmable instruction kit for stem cell function
Making brain stem cells act more like salmon than bloodhounds
Like salmon swimming against a river current, brain stem cells can travel against their normal migration stream with the help of electrical stimuli, so says CIRM-funded research published this week in Stem Cell Reports. The research, carried out by a team of UC Davis scientists, could one day provide a means for guiding brain stem … Continue reading Making brain stem cells act more like salmon than bloodhounds
Stories that caught our eye: An antibody that could make stem cell research safer; scientists prepare for clinical trial for Parkinson’s disease; and the stem cell scientist running for Congress
Antibody to make stem cells safer: There is an old Chinese proverb that states: ‘What seems like a blessing could be a curse’. In some ways that proverb could apply to stem cells. For example, pluripotent stem cells have the extraordinary ability to turn into many other kinds of cells, giving researchers a tool to … Continue reading Stories that caught our eye: An antibody that could make stem cell research safer; scientists prepare for clinical trial for Parkinson’s disease; and the stem cell scientist running for Congress
New stem cell technique gives brain support cells a starring role
Astrocytes are some of the most common cells in the brain and central nervous system but they often get overlooked because they play a supporting role to the more glamorous neurons (even though they outnumber them around 50 to 1). But a new way of growing those astrocytes outside the brain could help pave the … Continue reading New stem cell technique gives brain support cells a starring role
CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia
Imagine you’ve just stopped your car at the top of the steepest street in San Francisco. Now, if want to stay at the top of the hill you’re going to need to keep your foot on the brakes. Let go and you’ll start rolling down. Fast. Conceptually, similar decision points happen in human development. A … Continue reading CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia
Using stem cells to fix bad behavior in the brain
Diseases of the brain have many different names, from Alzheimer’s and Parkinson’s to ALS and Huntington’s, but they often have similar causes. Researchers at the Gladstone Institutes in San Francisco are using that knowledge to try and find an approach that might be effective against all of these diseases. In a new CIRM-funded study, … Continue reading Using stem cells to fix bad behavior in the brain
Translating great stem cell ideas into effective therapies
In science, there are a lot of terms that could easily mystify people without a research background; “translational” is not one of them. Translational research simply means to take findings from basic research and advance them into something that is ready to be tested in people in a clinical trial. Yesterday our Governing Board approved … Continue reading Translating great stem cell ideas into effective therapies
Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Glowing stem cells help scientists understand how cells work. (Karen Ring) It’s easy to notice when something is going wrong. It’s a lot harder to … Continue reading Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID
Measuring depression with non-invasive imaging of new brain cells
For most of the 20th century, scientists thought you’re basically stuck with the brain cells you’re born with. “Everything may die, nothing may be regenerated”, is how Santiago Ramón y Cajal, the father of modern neuroscience, described nerve cells, aka neurons, in the adult brain. But, over the past few decades, it’s become clear that … Continue reading Measuring depression with non-invasive imaging of new brain cells
The Stem Cellar 