This blog is part of our Month of CIRM series, which features our Agency’s progress towards achieving our mission to accelerate stem cell treatments to patients with unmet medical needs. This week, we’re highlighting CIRM-funded clinical trials to address the growing interest in our rapidly expanding clinical portfolio. Today we are featuring trials in our blood and … Continue reading CIRM-Funded Clinical Trials Targeting Blood and Immune Disorders
Author: Todd Dubnicoff
CIRM-Funded Clinical Trials Targeting Cancers
Welcome to the Month of CIRM! As we mentioned in last Thursday’s blog, during the month of October we’ll be looking back at what CIRM has done since the agency was created by the people of California back in 2004. To start things off, we’ll be focusing on CIRM-funded clinical trials this week. Supporting clinical … Continue reading CIRM-Funded Clinical Trials Targeting Cancers
An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration
We’ve written many blogs over the years about research focused on muscle stem cell function . Those stories describe how satellite cells, another name for muscle stem cells, lay dormant but jump into action to grow new muscle cells in response to injury and damage. And when satellite function breaks down with aging as well as … Continue reading An unexpected link: immune cells send muscle injury signal to activate stem cell regeneration
Bioengineers make breathtaking step toward building a lung
Tissue engineers have made amazing progress when it comes to using stem cells to build tissues such as blood vessels, which have relatively simple tubular shape. In fact, a late stage CIRM-funded clinical trial run by Humacyte is testing an engineered vein to improve dialysis treatment for people with kidney disease. Building a lung that … Continue reading Bioengineers make breathtaking step toward building a lung
Blocking spike in stem cell growth after brain injury may lessen memory decline, seizures
Survivors of traumatic brain injury (TBI) often suffer from debilitating, life changing symptoms like memory decline and epileptic seizures. Researchers had observed that following TBI, a stem cell-rich area of the brain provides a spike in new nerve cell growth, presumably to help replace damaged or destroyed brain cells. But, like a lot of things … Continue reading Blocking spike in stem cell growth after brain injury may lessen memory decline, seizures
Attractive new regenerative medicine tool uses magnets to shape and stimulate stem cells
The ultimate goal of tissue engineers who work in the regenerative medicine field is to replace damaged or diseased organs with new ones built from stem cells. To accomplish the feat, these researchers are developing new tools and techniques to manipulate and specialize stem cells into three dimensional structures. Some popular methods – which we’ve … Continue reading Attractive new regenerative medicine tool uses magnets to shape and stimulate stem cells
UCLA launches CIRM-funded clinical trial using engineered blood stem cells to fight hard-to-treat cancers
It’s not uncommon for biomedical institutes as well as their funding partners to announce through press releases that a clinical trial they’re running has gotten off the ground and has started to enroll patients. For an outsider looking in, it may seem like they’re jumping the gun a bit. No patients have received the therapy. … Continue reading UCLA launches CIRM-funded clinical trial using engineered blood stem cells to fight hard-to-treat cancers
Taming the Zika virus to kill cancer stem cells that drive lethal brain tumor
An out of control flame can be very dangerous, even life-threatening. But when harnessed, that same flame sustains life in the form of warm air, a source of light, and a means to cook. A similar duality holds true for viruses. Once it infects the body, a virus can replicate like wildfire and cause serious … Continue reading Taming the Zika virus to kill cancer stem cells that drive lethal brain tumor
Stories that caught our eye last week: dying cells trigger stem cells, CRISPR videogames and an obesity-stem cell link
A dying cell’s last breath triggers stem cell division. Most cells in your body are in a constant state of turnover. The cells of your lungs, for instance, replace themselves every 2 to 3 weeks and, believe it or not, you get a new intestine every 2 to 3 days. We can thank adult stem cells … Continue reading Stories that caught our eye last week: dying cells trigger stem cells, CRISPR videogames and an obesity-stem cell link
Extra dose of patience needed for spinal cord injury stem cell therapies, rat study suggests
2017 has been an exciting year for Asterias Biotherapeutics’ clinical trial which is testing a stem cell-based therapy for spinal cord injury. We’ve written several stories about patients who have made remarkable recoveries after participating in the trial (here and here). But that doesn’t mean researchers at other companies or institutes who are also investigating spinal … Continue reading Extra dose of patience needed for spinal cord injury stem cell therapies, rat study suggests