How stem cells know the right way to make a heart . And what goes wrong when they don’t

Gladstone scientists Deepak Srivastava (left), Yvanka De Soysa (center), and Casey Gifford (right) publish a complete catalog of the cells involved in heart development. The invention of GPS navigation systems has made finding your way around so much easier, providing simple instructions on how to get from point A to point B. Now, a new … Continue reading How stem cells know the right way to make a heart . And what goes wrong when they don’t

CIRM Board Approves $19.7 Million in Awards for Translational Research Program

In addition to approving funding for breast cancer related brain metastases last week, the CIRM Board also approved an additional $19.7 million geared towards our translational research program. The goal of this program is to help promising projects complete the testing needed to begin talking to the US Food and Drug Administration (FDA) about holding … Continue reading CIRM Board Approves $19.7 Million in Awards for Translational Research Program

CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases

Dr. Saul Priceman Yesterday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $9.28 million to Dr. Saul Priceman at City of Hope to conduct a clinical trial for the treatment of breast cancer related brain metastases, which are tumors in the brain that have spread from the original site of the … Continue reading CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases

Genetic defect leads to slower production of brain cells linked to one form of autism

Child with Fragile X syndrome Fragile X syndrome (FXS) is a genetic disorder that is the most common form of inherited intellectual disability in children, and has also been linked to a form of autism. Uncovering the cause of FXS could help lead to a deeper understanding of autism, what causes it and ultimately, it’s … Continue reading Genetic defect leads to slower production of brain cells linked to one form of autism

CIRM funded study identifies potential drug target for deadly heart condition

Joseph Wu is co-senior author of a study that demonstrates how patient-derived heart cells can help scientists better study the heart and screen potential therapies. Photo courtesy of Steve Fisch Heart disease continues to be the number one cause of death in the United States. An estimated 375,000 people have a genetic form of heart … Continue reading CIRM funded study identifies potential drug target for deadly heart condition

From bench to bedside: a Q&A with stem cell expert Jan Nolta

At CIRM we are privileged to work with many remarkable people who combine brilliance, compassion and commitment to their search for new therapies to help people in need. One of those who certainly fits that description is UC Davis' Jan Nolta. This week the UC Davis Newsroom posted a great interview with Jan. Rather than … Continue reading From bench to bedside: a Q&A with stem cell expert Jan Nolta

Tracking and mapping the health of damaged organs

Tissue engineering Medical treatments for a variety of diseases have advanced dramatically in recent decades, but sometimes they come with a cost; namely damage to surrounding tissues and organs. That’s where stem cell research and regenerative medicine come in. Those fields seek to develop new ways of repairing the damage. But how do you see … Continue reading Tracking and mapping the health of damaged organs

New study points to potential treatment for balance disorders

Alan Cheng and his colleagues were able to regenerate hair cells inside the ears of mice — a first in mature mammals. Photo Courtesy of Steve Fisch A sense of balance is important for a wide range of activities, from simple ones such as walking, running, and driving, to more intricate ones such as dancing, … Continue reading New study points to potential treatment for balance disorders

Getting the inside scoop on the stem cell agency

There’s a wonderful moment at the end of the movie The Candidate (starring Robert Redford, 87% approval on Rotten Tomatoes!) about a modern political campaign for a US Senate seat. Redford (spoiler alert) plays a come-from-behind candidate and at the end when he wins he turns to his campaign manager and says “Now what?”. I … Continue reading Getting the inside scoop on the stem cell agency

Developing a non-toxic approach to bone-crushing cancers

When cancer spreads to the bone the results can be devastating Battling cancer is always a balancing act. The methods we use – surgery, chemotherapy and radiation - can help remove the tumors but they often come at a price to the patient. In cases where the cancer has spread to the bone the treatments … Continue reading Developing a non-toxic approach to bone-crushing cancers