A new stem cell derived tool for studying brain diseases

Sergiu Pasca’s three-dimensional culture makes it possible to watch how three different brain-cell types – oligodendrocytes (green), neurons (magenta) and astrocytes (blue) – interact in a dish as they do in a developing human  brain. Courtesy of the Pasca lab Neurological diseases are among the most daunting diagnoses for a patient to receive, because they … Continue reading A new stem cell derived tool for studying brain diseases

Stanford Scientist Sergiu Pasca Receives Prestigious Vilcek Prize for Stem Cell Research on Neuropsychiatric Disorders

Last month, we blogged about Stanford neuroscientist Sergiu Pasca and his interesting research using stem cells to model the human brain in 3D. This month we bring you an exciting update about Dr. Pasca and his work. On February 1st, Pasca was awarded one of the 2018 Vilcek Prizes for Creative Promise in Biomedical Science. … Continue reading Stanford Scientist Sergiu Pasca Receives Prestigious Vilcek Prize for Stem Cell Research on Neuropsychiatric Disorders

Modeling the Human Brain in 3D

Can you guess what the tiny white balls are in this photo? I’ll give you a hint, they represent the organ that you’re using right now to answer my question. These are 3D brain organoids generated from human pluripotent stem cells growing in a culture dish. You can think of them as miniature models of … Continue reading Modeling the Human Brain in 3D

Stem cell-derived, 3D brain tissue reveals autism insights

Studying human brain disorders is one of the most challenging fields in biomedical research. Besides the fact that the brain is incredibly complex, it’s just plain difficult to peer into it. For one thing, it’s not practical, let alone ethical, to drill into an affected person’s skull and collect brain cells to learn about their … Continue reading Stem cell-derived, 3D brain tissue reveals autism insights