Top left to right: Tomasz Nowakowski, PhD, and Nevan Krogan, PhD Bottom left to right: Aparna Bhaduri, PhD; Matt State, PhD; Alice Ting, PhD; Trey Ideker, PhD; Willow Coyote-Maestas, PhD As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our … Continue reading Using Genetic Sequencing and AI to Identify and Treat Schizophrenia
schizophrenia
CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism
From top left to right: Anne Bang, PhD; Carrie Bearden, PhD; Eugene Yeo, PhD; Jonathan Sebat, PhD Bottom left to right: Alysson Moutri, PhD; Lilia Iakoucheva, PhD; Sébastien Jacquemont; Trey Ideker, PhD This blog is part of a series highlighting our ReMIND program and the researchers it’s supporting. To explore all features in the series, … Continue reading CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism
Stem cell research reveals path to schizophrenia
3d illustration of brain nerve cells - Photo courtesy Science Photo If you don’t know what’s causing a problem it’s hard to come up with a good way to fix it. Mental health is the perfect example. With a physical illness you can see what the problem is, through blood tests or x-rays, and develop … Continue reading Stem cell research reveals path to schizophrenia
Stanford scientists link problems in nerve cells to schizophrenia
A spherical cluster of hundreds of thousands of brain cells cultured in a lab dish. A team of researchers studied such neuronal clusters to better understand schizophrenia.Image Credit: Pasca lab The neurological origins of mental illness continue to remain a mystery and along with it any potential treatments for these conditions. However, Dr. Sergiu Pasca … Continue reading Stanford scientists link problems in nerve cells to schizophrenia
“Brains” in a dish that can create electrical impulses
Brain organoids in a petri dish: photo courtesy UCSD For several years, researchers have been able to take stem cells and use them to make three dimensional structures called organoids. These are a kind of mini organ that scientists can then use to study what happens in the real thing. For example, creating kidney organoids … Continue reading “Brains” in a dish that can create electrical impulses
A future scientist’s journey
All this week we have been highlighting blogs from our SPARK (Summer Program to Accelerate Regenerative medicine Knowledge) students. SPARK gives high school students a chance to spend their summer working in a world class stem cell research facility here in California. In return they write about their experiences and what they learned. The standard … Continue reading A future scientist’s journey
Friday Stem Cell Roundup: Making Nerves from Blood; New Clues to Treating Parkinson’s
Stanford lab develops method to make nerve cells from blood. Back in 2010, Stanford Professor Marius Wernig and his team devised a method to directly convert skin cells into neurons, a nerve cell. This so-called transdifferentiation technique leapfrogs over the need to first reprogram the skin cells into induced pluripotent stem cells. This breakthrough provided … Continue reading Friday Stem Cell Roundup: Making Nerves from Blood; New Clues to Treating Parkinson’s
Stem Cell Roundup: better model of schizophrenia, fasting boosts stem cells, and why does our hair gray.
Stem cell photo of the week: Recreating brain cell interactions for studying schizophrenia Our pick for the stem cell image of the week is from the laboratory of Rusty Gage at the Salk Institute. The team generated multiple types of nerve cells from stem cells to more closely represent the interactions that occur in the … Continue reading Stem Cell Roundup: better model of schizophrenia, fasting boosts stem cells, and why does our hair gray.
Stem Cell Roundup: The brain & obesity; iPSCs & sex chromosomes; modeling mental illness
Stem Cell Image of the Week: Obesity-in-a-dish reveals mutations and abnormal function in nerve cells Our stem cell image of the week looks like the work of a pre-historic cave dweller who got their hands on some DayGlo paint. But, in fact, it’s a fluorescence microscopy image of stem cell-derived brain cells from the lab … Continue reading Stem Cell Roundup: The brain & obesity; iPSCs & sex chromosomes; modeling mental illness
CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia
Imagine you’ve just stopped your car at the top of the steepest street in San Francisco. Now, if want to stay at the top of the hill you’re going to need to keep your foot on the brakes. Let go and you’ll start rolling down. Fast. Conceptually, similar decision points happen in human development. A … Continue reading CIRM-funded team uncovers novel function for protein linked to autism and schizophrenia