THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Pong video game Back when I was growing up, shortly after the extinction of the dinosaurs, there was a popular video game called Pong. It was, in fact, pretty much the only video game at the time. It was a pretty simple game. You moved a “paddle” … Continue reading Teaching stem cells to play video games
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Reprogramming brain cells to restore vision after a stroke
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST About one third of stroke survivors experience vision loss. It can be a devastating side effect as most patients will not fully recover their vision and there are currently no reliable treatments available. But thanks to a collaborative effort by two teams of researchers from Purdue … Continue reading Reprogramming brain cells to restore vision after a stroke
Paving the way for a treatment for dementia
What happens in a stroke When someone has a stroke, the blood flow to the brain is blocked. This kills some nerve cells and injures others. The damaged nerve cells are unable to communicate with other cells, which often results in people having impaired speech or movement. While ischemic and hemorrhagic strokes affect large blood … Continue reading Paving the way for a treatment for dementia
Study shows connection between bipolar disorder and neuroinflammation
Astrocytes, which provide structural support and protection for neurons and also supply them with nutrients and oxygen. Bipolar disorder (BPD) is a mental disorder that causes unusual shifts in mood, energy, activity levels, concentration, and the ability to carry out day-to-day tasks. In the United States, recent research has shown that 1.6% of the population … Continue reading Study shows connection between bipolar disorder and neuroinflammation
CIRM funded researchers discover link between Alzheimer’s gene and COVID-19
Dr. Yanhong Shi (left) and Dr. Vaithilingaraja Arumugaswami (right) All this month we are using our blog and social media to highlight a new chapter in CIRM’s life, thanks to the voters approving Proposition 14. We are looking back at what we have done since we were created in 2004, and also looking forward to the … Continue reading CIRM funded researchers discover link between Alzheimer’s gene and COVID-19
Genetic defect leads to slower production of brain cells linked to one form of autism
Child with Fragile X syndrome Fragile X syndrome (FXS) is a genetic disorder that is the most common form of inherited intellectual disability in children, and has also been linked to a form of autism. Uncovering the cause of FXS could help lead to a deeper understanding of autism, what causes it and ultimately, it’s … Continue reading Genetic defect leads to slower production of brain cells linked to one form of autism
A new stem cell derived tool for studying brain diseases
Sergiu Pasca’s three-dimensional culture makes it possible to watch how three different brain-cell types – oligodendrocytes (green), neurons (magenta) and astrocytes (blue) – interact in a dish as they do in a developing human brain. Courtesy of the Pasca lab Neurological diseases are among the most daunting diagnoses for a patient to receive, because they … Continue reading A new stem cell derived tool for studying brain diseases
Using 3D printer to develop treatment for spinal cord injury
Spinal cord injuries (SCIs) affect approximately 300,000 Americans, with about 18,000 new cases occurring per year. One of these patients, Jake Javier, who we have written about many times over the past several years, received ten million stem cells as part of a CIRM-funded clinical trial and a video about his first year at Cal … Continue reading Using 3D printer to develop treatment for spinal cord injury
CIRM-funded research is helping unlock the secrets behind “chemo brain”
Every year millions of Americans undergo chemotherapy. The goal of the treatment is to destroy cancer, but along the way more than half of the people treated lose something else. They suffer from something called “chemo brain” which causes problems with thinking and memory. In some cases it can be temporary, lasting a few months. … Continue reading CIRM-funded research is helping unlock the secrets behind “chemo brain”
Japanese scientists implant first Parkinson’s patient with replacement neurons derived from stem cells
Currently, more than 10 million people worldwide live with Parkinson’s disease (PD). By 2020, in the US alone, people living with Parkinson’s are expected to outnumber the cases of multiple sclerosis, muscular dystrophy and Lou Gehrig’s disease combined. There is no cure for Parkinson’s and treatment options consist of medications that patients ultimately develop tolerance … Continue reading Japanese scientists implant first Parkinson’s patient with replacement neurons derived from stem cells
The Stem Cellar 