Repairing, even reversing, the damage caused by a heart attack is the Holy Grail of stem cell researchers. For years the Grail seemed out of reach because the cells that researchers transplanted into heart attack patients didn’t stick around long enough to do much good. Now researchers at Stanford may have found a way around … Continue reading Creating a platform to help transplanted stem cells survive after a heart attack
Joseph Wu
Researchers, beware: humanized mice not human enough to study stem cell transplants
A researcher’s data is only as good as the experimental techniques used to obtain those results. And a Stanford University study published yesterday in Cell Reports, calls into question the accuracy of a widely used method in mice that helps scientists gauge the human immune system’s response to stem cell-based therapies. The findings, funded in … Continue reading Researchers, beware: humanized mice not human enough to study stem cell transplants
Stem cell stories that caught our eye: drug safety for heart cells, worms hijack plant stem cells & battling esophageal cancer
Devising a drug safety measuring stick in stem cell-derived heart muscle cells One of the mantras in the drug development business is “fail early”. That’s because most of the costs of getting a therapy to market occur at the later stages when an experimental treatment is tested in clinical trials in people. So, it’s best … Continue reading Stem cell stories that caught our eye: drug safety for heart cells, worms hijack plant stem cells & battling esophageal cancer
Curing the Incurable through Definitive Medicine
“Curing the Incurable”. That was the theme for the first annual Center for Definitive and Curative Medicine (CDCM) Symposium held last week at Stanford University, in Palo Alto, California. The CDCM is a joint initiative amongst Stanford Healthcare, Stanford Children’s Health and the Stanford School of Medicine. Its mission is to foster an environment that … Continue reading Curing the Incurable through Definitive Medicine
Stem cell stories that caught our eye: two studies of the heart and cool stem cell art
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Understanding Heart Defects. Healthy heart tissue is made up of smooth, solid muscle, which is essential for normal heart function. Patients with a heart defect … Continue reading Stem cell stories that caught our eye: two studies of the heart and cool stem cell art
CIRM Grantees Reflect on Ten Years of iPS Cells
For the fourth entry for our “Ten Years of Induced Pluripotent Stem (iPS) Cells” series, which we’ve been posting all month, I reached out to three of our CIRM grantees to get their perspectives on the impact of iPSC technology on their research and the regenerative medicine field as a whole: Step back in time … Continue reading CIRM Grantees Reflect on Ten Years of iPS Cells
Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk
The good news is you’re cancer free, the bad news is you need a heart transplant. It almost sounds like the punchline to a joke, but it’s no laugher matter because the scenario is real for some cancer patients. Chemotherapy is a life saver for many but certain doses can be so toxic that it’s often hard … Continue reading Chemo-Induced Heart Failure: Using Stem Cells to Identify Those at Risk
Stem Cells become Tool to Screen for Drugs; Fight Dangerous Heart Infections.
A Stanford study adds a powerful example to our growing list of diseases that have yielded their secrets to iPS-type stem cells grown in a dish. These “disease-in-a-dish” models have become one of the most rapidly growing areas of stem cell science. But this time they did not start with skin from a patient with … Continue reading Stem Cells become Tool to Screen for Drugs; Fight Dangerous Heart Infections.
What a Difference Differentiation can Make: a Little Change can Reduce the Risk of Rejection
No one likes to be rejected. It hurts. But while rejection is something most of us experience at least a couple of times in our life, researchers at Stanford have found a way to reduce the risk of rejection, at least when it comes to one form of stem cells. Reporting in the latest issue … Continue reading What a Difference Differentiation can Make: a Little Change can Reduce the Risk of Rejection
The Stem Cellar 